ReviewOpen access Macedonian journal of medical sciences2019
Systematic Review of Prevalence of Antepartum Depression during the Trimesters of Pregnancy.
Review in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it, 173 citations in OpenAlex.
- Pooled it
- The Impact of Mindfulness-Based Counseling on the Mental Health of Women With a History of COVID-19 During Pregnancy: A Quasi-Experimental Study.Brain and behavior · 2024Trial
- Maternal anxiety or depression and cognitive ability in young male offspring: A population-based cohort study using cognitive test scores from the Danish Conscription Board Examination.Social psychiatry and psychiatric epidemiology · 2026Article
- To Climb or Not to Climb: A Cross-Sectional Investigation of Risks and Benefits During Pregnancy and Postpartum.Sports medicine (Auckland, N.Z.) · 2026Article
- Evaluation of Vortioxetine on Global DNA Methylation in Maternal and Offspring Rats and In Silico Molecular Docking to Key Epigenetic Enzymes.International journal of molecular sciences · 2026Article
- Perinatal HPA axis regulation and offspring neuropsychiatric development: mechanisms, developmental trajectories, and clinical implications.Frontiers in endocrinology · 2026Review
- Development and Internal Validation of a Psychosocial Nomogram for Antenatal Depressive Symptoms in Third-Trimester Pregnant Women at a Regional Hospital in Southern Vietnam.International journal of women's health · 2026Article
- Research on the construction of prediction model for depressive symptom in the second and third trimester of pregnancy based on artificial neural network.Frontiers in psychiatry · 2026Article
- What are the Risks of Contact Sport During Pregnancy: a Survey-Based Investigation.Sports medicine (Auckland, N.Z.) · 2025Article
- Effect of gestational anemia on breastfeeding- a prospective follow-up -study.BMC pregnancy and childbirth · 2025Article
- Investigating the Microbiome in Relation to Mental Distress Across Two Points During Pregnancy: Data From U.S. and Swedish Cohorts.Biological psychiatry global open science · 2025Article
- The effects of maternal health literacy, family functioning and self-efficacy on antepartum depression in pregnant women in China: a moderated mediation model.BMC psychiatry · 2025Article
- Measuring psychological well-being in a danish pregnancy cohort using the self-reported WHO-5 index.BMC psychology · 2025Article
- Improving postnatal social support using antenatal group-based psychoeducation: a cluster randomized controlled trial.Frontiers in global women's health · 2025Article
- Prevalence and Factors Associated With Antepartum Depression Among Pregnant Women in Latent Labor: A Multi-Facility Cross-Sectional Study in Rural Southwestern Uganda.International journal of women's health · 2025Article
- The prevalence and associated factors of third-trimester pregnancy depression in pre-pregnancy overweight and obesity women: a cross-sectional study in Guangdong, China.Frontiers in public health · 2025Article
- Article
- Gestational diabetes mellitus and peripartum depression: a longitudinal study of a bidirectional relationship.BMC pregnancy and childbirth · 2024Article
- Risk factors of the antenatal depression in a sample of Italian pregnant women: a preliminary study.BMC pregnancy and childbirth · 2024Article
- The Application of Engineered Nanomaterials in Perinatal Therapeutics.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression is prevalent during antenatal and postnatal stages of pregnancy. The effect of depression can be seen in complications during and after pregnancy, fetal growth retardation, abortions and preterm births. The literature abounds on postpartum depression (PD) while few studies are on antepartum depression (AD).
aimThe systematic review aims to compute the prevalence of AD from published articles. MATERIAL AND
methodsThe published articles (26) used in this review were obtained from the search of the search keywords "Depressive conditions in pregnancy AND trimesters". All the articles were considered irrespective of language and their citation status as of the time of the query. Only articles that presented the prevalence mean and sample size were included. Articles on questionnaires filled by nonpregnant women and men were excluded. Articles that presented the prevalence of depression for the postpartum period only were excluded but were included if they addressed depression at both postpartum and trimester(s) of pregnancy. P-value of less than or equal to 0.05 was considered significant.
resultsAnalysis of the 26 articles showed that 4,303 subjects tested positive for depression in a sample of 28,248 pregnant mothers, giving the prevalence rate as 15%. Confounding was removed, and the sample size was adjusted to be 25,771 and 4,223 were screened to have depressive symptoms, thereby giving a new prevalence rate as 16.4%. It was also revealed that AD is most prevalent in the last trimester of pregnancy and least in the second trimester. Pregnancy duration and PD are not correlated with AD. This implies that AD can be observed in any period of the pregnancy and cannot predict the incidence of PD.
conclusionEfforts must be intensified to monitor pregnant women during the third trimester to reduce the incidence of maternal depression during pregnancy, thereby reducing the prevalence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.