Evidence map›Paper›PMID 31198446›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Seluang Fish (

Radiyati Umi Partan, Rachmat Hidayat, Nurwan Saputra, Febry Rahmayani, Hari Prapto, Timotius Wira Yudha

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06659068 (Efficacy of Seluang Fish Oil), which is not on this map. Cited by 12 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 6 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06659068 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy of Seluang Fish Oil (Rasbora Argyrotaenia) and Synbiotics Supplementation on CD4+CD25+ Foxp3+ T-regulator Cells, IL17/IL-10 Ratio, and Disease Activity in Systemic Lupus Erythematosus Patients

TypeinterventionalSponsorUniversitas SriwijayaRan2024 to 2025Enrolled40ConditionsSystemic Lupus Erythematosus (SLE)ArmsSeluang fish oil (Rasbora argyrotaenia) and synbiotic, Placebo
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 6 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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  5. Interventions for cutaneous disease in systemic lupus erythematosus.The Cochrane database of systematic reviews · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Radiyati Umi PartanInternal Medicine Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Rachmat HidayatBiology Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Nurwan SaputraInternal Medicine Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Febry RahmayaniInternal Medicine Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Hari PraptoInternal Medicine Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Timotius Wira YudhaBiology Department, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Sriwijaya University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic Lupus Erythematosus (SLE) is an autoimmune disorder mediated by inflammatory cytokines. Decreasing vitamin D levels is a common feature in SLE patients. Vitamin D has the capacity in suppressing inflammatory cascade. Seluang fish (

aimThis study aimed to assess the efficacy of Seluang fish oil against proinflammatory cytokines, vitamin D levels, and clinical conditions of SLE.

methodsA randomised, double-blind, clinical trial study design was conducted. The subjects were 16 SLE subjects treated with 500uL Seluang fish oil capsules and 16 SLE subjects with placebo capsules. Measurement of vitamin D, IL-1, IL-6 and IL-17 levels were performed with ELISA. Clinical assessment of SLE was performed with MEX-SLEDAI. Bivariate analysis, T-test, was performed. Data were presented in the form of mean ± SD.

resultsThe administration of Seluang fish oil was clinically able to show efficacy assessed by the MEX SLEDAI score. Significant results were also shown by increased vitamin D levels and reduced levels of IL-1, IL-6 and IL-17, in Seluang fish oil group.

conclusionSeluang fish oil possessed the efficacy of reducing the inflammatory response in SLE patients by increasing serum vitamin D levels.

Indexed as

Inflammatory cytokinesRasbora sppSeluang fish oilSystemic Lupus ErythematosusVitamin D

Identifiers

PMID31198446
PMCPMC6542399
OpenAlexW2942776989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.