Evidence map›Paper›PMID 31198082›Full record

ReviewChannels (Austin, Tex.)2019

Airway regeneration using iPS cell-derived airway epithelial cells with Cl

Susumu Yoshie, Koichi Omori, Akihiro Hazama

Open access · goldAbstract readReview
In one paragraph

Review in Channels (Austin, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Susumu Yoshiea Department of Cellular and Integrative Physiology, School of Medicine , Fukushima Medical University , Fukushima , Japan.
Koichi Omorib Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine , Kyoto University , Kyoto , Japan.
Akihiro Hazamaa Department of Cellular and Integrative Physiology, School of Medicine , Fukushima Medical University , Fukushima , Japan.
Fukushima Medical University · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

induced pluripotent stem (iPS) cells can be differentiated into various cell types, including airway epithelial cells, since they have the capacity for self-renewal and pluripotency. Thus, airway epithelial cells generated from iPS cells are expected to be potent candidates for use in airway regeneration and the treatment of airway diseases such as cystic fibrosis (CF). Recently, it was reported that iPS cells can be differentiated into airway epithelial cells according to the airway developmental process. These studies demonstrate that airway epithelial cells generated from iPS cells are equivalent to their in vivo counterparts. However, it has not been evaluated in detail whether these cells exhibit physiological functions and are fully mature. Airway epithelial cells adequately control water volume on the airway surface via the function of Cl

Indexed as

AnimalsCell DifferentiationChloride ChannelsChloridesEpithelial CellsHumansInduced Pluripotent Stem CellsLungRegenerationChloride ChannelsChloridesairway epithelial cellsCFTRCl channelcystic fibrosisiPS cells

Identifiers

PMID31198082
PMCPMC6602574
OpenAlexW2949156794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.