Evidence map›Paper›PMID 31197983›Full record

ArticleJournal of Korean medical science2019

Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis.

Young Dai Kwon, Kyung Ok Ko, Jae Woo Lim, Eun Jung Cheon, Young Hwa Song, Jung Min Yoon

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Correlation between Transient Elastography (FibroscanPediatric gastroenterology, hepatology & nutrition · 2022
    Article
  15. [Study on the diagnostic value of transient elastography, APRI and FIB-4 for liver fibrosis in children with non-alcoholic fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Young Dai KwonDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-9051-5937
Kyung Ok KoDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4407-9534
Jae Woo LimDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-2001-0727
Eun Jung CheonDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-3844-0864
Young Hwa SongDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-6837-0599
Jung Min YoonDepartment of Pediatrics, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea. jmyoon@kyuh.ac.kr.ORCID https://orcid.org/0000-0003-3496-0061

Funding

National Research Foundation of Korea NRF-2017R1C1B5076076
6 · The paper itself

Abstract

backgroundTransient elastography (FibroScan®) is a non-invasive and rapid method for assessing liver fibrosis. While the feasibility and usefulness of FibroScan® have been proven in adults, few studies have focused on pediatric populations. We aimed to determine the feasibility and usefulness of FibroScan® in Korean children.

methodsFibroScan® examinations were performed in 106 children (age, 5-15 years) who visited the Konyang University Hospital between June and September 2018. Liver steatosis was measured in terms of the controlled attenuation parameter (CAP), while hepatic fibrosis was evaluated in terms of the liver stiffness measurement (LSM). Children were stratified into obese and non-obese controls, according to body mass index (≥ or < 95th percentile, respectively).

resultsThe obese group was characterized by significantly higher levels of aspartate aminotransferase (AST, 57.00 ± 48.47 vs. 26.40 ± 11.80 IU/L;

conclusionFibroScan® is clinically feasible and facilitates non-invasive, rapid, reproducible, and reliable detection of hepatic steatosis and liver fibrosis in the Korean pediatric population.

Indexed as

AdolescentAlanine TransaminaseAspartate AminotransferasesBody Mass IndexChildChild, PreschoolElasticity Imaging TechniquesFemalegamma-GlutamyltransferaseHumansLiver CirrhosisMaleNon-alcoholic Fatty Liver DiseaseObesityAlanine TransaminaseAspartate Aminotransferasesgamma-GlutamyltransferaseChildLiver FibrosisNonalcoholic Fatty Liver DiseaseNon-Invasive Diagnosis

Identifiers

PMID31197983
PMCPMC6565925

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.