ArticleBrain and behavior2019
Plasma Brain-Derived Neurotrophic Factor (BDNF) and serum cortisol levels in a sample of workers exposed to occupational stress and suffering from Adjustment Disorders.
Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Serum Brain-derived Neurotrophic Factor, Stress Levels, and Quality of Life Among Leprosy Patients: A Cross-sectional Study.Acta dermato-venereologica · 2026Article
- Emotional Dysregulation and Stress-Related Psychopathology in Workers Exposed to Occupational Stress.Behavioral sciences (Basel, Switzerland) · 2026Article
- The role of the neuroinflammation and stressors in premenstrual syndrome/premenstrual dysphoric disorder: a review.Frontiers in endocrinology · 2025Review
- Plasma Brain-Derived Neurotrophic Factor (BDNF) Levels and BDNF Promoters' DNA Methylation in Workers Exposed to Occupational Stress and Suffering from Psychiatric Disorders.Brain sciences · 2024Article
- Plasma and Platelet Brain-Derived Neurotrophic Factor (BDNF) Levels in Bipolar Disorder Patients with Post-Traumatic Stress Disorder (PTSD) or in a Major Depressive Episode Compared to Healthy Controls.International journal of molecular sciences · 2024Article
- Salivary Brain-Derived Neurotrophic Factor and Cortisol Associated with Psychological Alterations in University Students.Diagnostics (Basel, Switzerland) · 2024Article
- Association between salivary mature brain-derived neurotrophic factor and psychological distress in healthcare workers.Brain and behavior · 2023Article
- Variation of Circulating Brain-Derived Neurotrophic Factor (BDNF) in Depression: Relationships with Inflammatory Indices, Metabolic Status and Patients' Clinical Features.Life (Basel, Switzerland) · 2023Article
- Elevations in serum brain-derived neurotrophic factor following occupational heat stress are not influenced by age or common chronic disease.Temperature (Austin, Tex.) · 2023Article
- Intimate partner violence: psycho-physio-pathological sequelae for defining a holistic enriched treatment.Frontiers in behavioral neuroscience · 2022Article
- Sex-specific association of high maternal psychological stress during pregnancy on newborn birthweight.PloS one · 2022Article
- Mental health of Health Care Workers (HCWs): a review of organizational interventions put in place by local institutions to cope with new psychosocial challenges resulting from COVID-19.Psychiatry research · 2021Review
- Diazepam ameliorates altered proinflammatory and cardiac markers in stress exposed rats.Saudi journal of biological sciences · 2021Article
- Potential biomarkers of emotional stress induced neurodegeneration.eNeurologicalSci · 2020Review
- Professional Quality of Life and Mental Health Outcomes among Health Care Workers Exposed to Sars-Cov-2 (Covid-19).International journal of environmental research and public health · 2020Article
- State-of-the-Art: Inflammatory and Metabolic Markers in Mood Disorders.Life (Basel, Switzerland) · 2020Review
- Plasma Brain-Derived Neurotrophic Factor (BDNF) and serum cortisol levels in a sample of workers exposed to occupational stress and suffering from Adjustment Disorders.Brain and behavior · 2019Article
- Perceived Stress and Cfognition Function Quantification in a Scary Video Game: An Electroencephalogram Features and Biochemical Measures.Basic and clinical neuroscienceArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDecreased plasma BDNF (pBDNF) levels have been proposed as a biomarker in illness phases of mood disorders. Serum cortisol (seC) levels are an index of energy mobilization and stress. The aim of this cross-sectional study was to evaluate pBDNF and seC levels in workers exposed to occupational stress and suffering from Adjustment Disorders (AD) compared to healthy workers.
methodsPlasma BDNF and seC levels were measured by means of specific immunoassays in 64 AD patients and 38 healthy controls. Perceived and occupational stress was evaluated in patients and controls using the Psychological Stress Measure (PSM) and the Job Content Questionnaire (JCQ). Psychopatological symptoms in patients were assessed using specific rating scales.
resultsPlasma BDNF levels resulted significantly higher in patients than in controls, whereas no significant differences were found for seC levels. In patients but not in controls pBDNF levels showed a significant positive correlation with seC levels. Perceived stress levels were positively correlated with all psychopatological rating scales scores.
conclusionsBDNF could play a key role in the pathophysiology of stress-related disorders and its peripheral levels elevation could contribute to protect neurons under stress. Further research is needed focusing on biomarkers for stress-related disorders as a potential tool for the diagnosis and prevention of occupational diseases.
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