Evidence map›Paper›PMID 31197539›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Palliative care needs of advanced cancer patients in the emergency department at the end of life: an observational cohort study.

Mary-Joanne Verhoef, Ellen de Nijs, Nanda Horeweg, Jaap Fogteloo, Christian Heringhaus, Anouk Jochems, Marta Fiocco, Yvette van der Linden

Abstract readObservational Study
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Characteristics associated with accepting hospital at home among patients with cancer and their caregivers: a cross-sectional survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. [Patients with cancer: a challenge for emergency departments].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mary-Joanne VerhoefCenter of Expertise Palliative Care, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands. m.verhoef@lumc.nl.ORCID http://orcid.org/0000-0002-3796-815X
Ellen de NijsCenter of Expertise Palliative Care, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Nanda HorewegDepartment of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands.
Jaap FogtelooDepartment of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Christian HeringhausDepartment of Emergency Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Anouk JochemsDepartment of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands.
Marta FioccoDepartment of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
Yvette van der LindenCenter of Expertise Palliative Care, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with advanced cancer commonly visit the emergency department (ED) during the last 3 months of life. Identification of these patients and their palliative care needs help initiating appropriate care according to patients' wishes. Our objective was to provide insight into ED visits of advanced cancer patients at the end of life.

methodsAdult palliative patients with solid tumours who died < 3 months after their ED visit were included (2011-2014). Patients, ED visits, and follow-up were described. Factors associated with approaching death were assessed using Cox proportional hazards models.

resultsFour hundred twenty patients were included, 54.5% was male, median age 63 years. A total of 54.6% was on systemic anti-cancer treatments and 10.5% received home care ≥ 1 per day. ED visits were initiated by patients and family in 34.0% and 51.9% occurred during out-of-office hours. Dyspnoea (21.0%) or pain (18.6%) were most reported symptoms. Before the ED visit, limitations on life-sustaining treatments were discussed in 33.8%, during or after the ED visit in 70.7%. Median stay at the ED was 3:29 h (range 00:12-18:01 h), and 319 (76.0%) were hospitalized. Median survival was 18 days (IQ range 7-41). One hundred four (24.8%) died within 7 days after the ED visit, of which 71.2% in-hospital. Factors associated with approaching death were lung cancer, neurologic deterioration, dyspnoea, hypercalcemia, and jaundice.

conclusionED visits of advanced cancer patients often lead to hospitalization and in-hospital deaths. Timely recognition of patients with limited life expectancies and urgent palliative care needs, and awareness among ED staff of the potential of ED-initiated palliative care may improve the end-of-life trajectory of these patients.

Indexed as

AdultAgedAged, 80 and overCohort StudiesEmergency Service, HospitalFemaleHospitalizationHumansMaleMiddle AgedNeeds AssessmentNeoplasmsPalliative CareProportional Hazards ModelsRetrospective StudiesTerminal CareEmergency departmentOncologyPalliative careTerminal care

Identifiers

PMID31197539
PMCPMC6989579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.