ReviewActa neuropathologica2019
Neurotoxicity of pesticides.
Review in Acta neuropathologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
168 citing papers in PubMed, 2 syntheses or guidelines pooled it, 501 citations in OpenAlex.
- Occupational exposure to pesticides increases the risk of amyotrophic lateral sclerosis: a systematic review and meta-analysis.Occupational and environmental medicine · 2026Pooled it
- Neurobehavioral effects of fungicides in zebrafish: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Carpal tunnel syndrome and exposure to work-related biomechanical stressors and chemicals: Findings from the Constances cohort.PloS one · 2020Trial
- Timing of exposure impacts how organophosphorus pesticides affect the developing brain in the planarian Dugesia japonica.Archives of toxicology · 2026Article
- Pesticides-induced cellular toxicity in the spinal cord cell line of Lates calcarifer.In vitro cellular & developmental biology. Animal · 2026Article
- Prevalent detection of multiclass environmental chemicals in paired CSF and plasma samples and their potential associations with postpartum depressive symptoms in pregnant women.Environmental research · 2026Article
- Field-deployable supramolecular fluorescent sensing platform for selective dual-mode detection of thiamethoxam in complex environmental matrices.Mikrochimica acta · 2026Article
- Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006-2020).Journal of exposure science & environmental epidemiology · 2026Article
- Chemicals in cow milk and soy beverages: Neurotoxicity and neuroprotection.Advances in neurotoxicology · 2026Article
- Neuroprotection Against a Panel of Toxicants via a Novel Analog of the Natural Product Fraxinellone.Chemical research in toxicology · 2026Article
- Effects of Pesticide Exposure on Cognitive Functions in Agricultural Workers: A Systematic Review.Florence Nightingale journal of nursing · 2026Article
- Spermidine Suppresses Peripheral Inflammation and Alleviates Non-Motor Symptoms in the 6-OHDA-Induced Rat Model of Parkinson's Disease.Molecules (Basel, Switzerland) · 2026Article
- Review
- Review
- Molecular characterization ofOpen veterinary journal · 2026Article
- Visual-acoustic thigmotaxis in zebrafish larvae: a high throughput NAM for neurotoxicity assessment.Frontiers in toxicology · 2026Article
- Epidemiological Insights into Xenobiotic-Induced Seizures: A Correlational Descriptive Study from a Poisoning Referral Center in Northwestern Iran.Medical journal of the Islamic Republic of Iran · 2026Article
- Transgenerational Consequences of Imidacloprid Larval Diet Contamination in the Sheep BlowflyInsects · 2025Article
- Artificial intelligence in clinical toxicology in Africa: Emerging applications and barriers.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025Review
- Attenuating Neurotoxicity Through Fecal Microbiota Transplant: Mechanisms and Therapeutic Potential.Molecular neurobiology · 2025Review
108 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
Pesticides are unique environmental contaminants that are specifically introduced into the environment to control pests, often by killing them. Although pesticide application serves many important purposes, including protection against crop loss and against vector-borne diseases, there are significant concerns over the potential toxic effects of pesticides to non-target organisms, including humans. In many cases, the molecular target of a pesticide is shared by non-target species, leading to the potential for untoward effects. Here, we review the history of pesticide usage and the neurotoxicity of selected classes of pesticides, including insecticides, herbicides, and fungicides, to humans and experimental animals. Specific emphasis is given to linkages between exposure to pesticides and risk of neurological disease and dysfunction in humans coupled with mechanistic findings in humans and animal models. Finally, we discuss emerging techniques and strategies to improve translation from animal models to humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.