ArticleScientific reports2019
Patient-specific Computational Hemodynamic Analysis for Interrupted Aortic Arch in an Adult: Implications for Aortic Dissection Initiation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Surgical Repair of a Giant Aberrant Artery Aneurysm in an Adult with Type B Interrupted Aortic Arch.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- Retearing of type B blind cystic aortic dissection: computational fluid dynamics analysis.Physical and engineering sciences in medicine · 2025Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- Estimating flow division in aortic branches of diseased aorta: a method for boundary condition specification in CFD analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Patient-Specific Haemodynamic Analysis of Virtual Grafting Strategies in Type-B Aortic Dissection: Impact of Compliance Mismatch.Cardiovascular engineering and technology · 2024Article
- A Case of Interrupted Aortic Arch in an Adult: An Unsuspected Cause of Uncontrolled Hypertension.Case reports in radiology · 2024Article
- Combined Curvature and Wall Shear Stress Analysis of Abdominal Aortic Aneurysm: An Analysis of Rupture Risk Factors.Cardiovascular and interventional radiology · 2022Article
- Computational Fluid Dynamics to Assess the Future Risk of Ascending Aortic Aneurysms.Arquivos brasileiros de cardiologia · 2022Observational
- Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator-regression neural network.Journal of the Royal Society, Interface · 2022Article
- A novel MRI-based data fusion methodology for efficient, personalised, compliant simulations of aortic haemodynamics.Journal of biomechanics · 2021Article
- The effect of beta-blockers on hemodynamic parameters in patient-specific blood flow simulations of type-B aortic dissection: a virtual study.Scientific reports · 2021Article
- Isolated interrupted aortic arch in an adult: A case report.World journal of clinical cases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The guideline for the treatment of interrupted aortic arch (IAA) in adults has not been established although most centers tend to propose surgery. There is no clear evidence for the preferred selection of surgical repair versus conservatively medical treatment for the uncertain effects of both treatments. However, reports of sporadic aortic dissection (AD) of descending aorta (DAo) in IAA in adults before surgery drew our attention. It is quite perplexing because there seems to be no risk factors for the development of AD at DAo such as long-term uncontrolled hypertension, atherosclerosis, aortic aneurysm or genetic disorder. In this paper, we carried out the numerical investigation on the hemodynamics in a patient-specific IAA model, which was reconstructed from computed tomography images. Hemodynamic parameters including the flow pattern, pressure distribution, and wall shear stress (WSS) indicators were obtained. The simulation revealed that the jet flows from the collateral arteries (CAs) induced risk hemodynamic forces on the lumen wall including high time-averaged wall shear stress (TAWSS), high pressure and rapid change of WSS direction throughout the cardiac cycle. Moreover, it is found that only a jet flow which circumferentially washes out the aortic wall might cause tears on the wall. It is concluded that the specific geometrical features of the extensive major CAs might result in the risky hemodynamics leading to the initiation and development of AD in this particular IAA patient. CFD analysis in IAA can provide a clinical reference, and the results should be further studied in depth in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.