Evidence map›Paper›PMID 31197206›Full record

ArticleScientific reports2019

A six-months study on Black Soldier Fly (Hermetia illucens) based diets in zebrafish.

Matteo Zarantoniello, Basilio Randazzo, Cristina Truzzi, Elisabetta Giorgini, Claudia Marcellucci, Jorge Arturo Vargas-Abúndez, Andrea Zimbelli, Anna Annibaldi, Giuliana Parisi, Francesca Tulli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 100 citations in OpenAlex.

  1. Full-Fat Black Soldier Fly Larvae Meal in Diets for Pacu,Animals : an open access journal from MDPI · 2026
    Article
  2. Effects of Black Soldier Fly Larval (Aquaculture nutrition · 2026
    Article
  3. Article
  4. Valorization of Agricultural Residues Through Nutrient Enrichment for Animal Farming.Advances in biochemical engineering/biotechnology · 2026
    Review
  5. Effects of Black Soldier Fly (Antioxidants (Basel, Switzerland) · 2025
    Article
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  13. Influence ofAnimals : an open access journal from MDPI · 2023
    Article
  14. Spirulina-enriched Substrate to Rear Black Soldier Fly (Animals : an open access journal from MDPI · 2023
    Article
  15. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Matteo ZarantonielloDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Basilio RandazzoDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Cristina TruzziDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Elisabetta GiorginiDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Claudia MarcellucciDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Jorge Arturo Vargas-AbúndezDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.ORCID http://orcid.org/0000-0001-7304-6016
Andrea ZimbelliDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Anna AnnibaldiDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Giuliana ParisiDipartimento di Scienze delle Produzioni Agroalimentari e dell'Ambiente (DISPAA), Università di Firenze, via delle Cascine 5, 50144, Firenze, Italy.
Francesca TulliDipartimento di Scienze Agroalimentari, Ambientali e Animali (Di4A), Università di Udine, via Sondrio, 2, 33100, Udine, Italy.
Paola RioloDipartimento di Scienze Agrarie, Alimentari ed Ambientali, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy.
Ike OlivottoDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, via Brecce Bianche, 60131, Ancona, Italy. i.olivotto@univpm.it.
Marche Polytechnic University · ITUniversity of Florence · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intensive fish farming relies on the use of feeds based on fish meal and oil as optimal ingredients; however, further development of the aquaculture sector needs new, nutritious and sustainable ingredients. According to the concept of circular economy, insects represent good candidates as aquafeed ingredients since they can be cultured through environmental-friendly, cost-effective farming processes, on by-products/wastes, and many studies have recently been published about their inclusion in fish feed. However, information about the physiological effects of insect-based diets over the whole life cycle of fish is presently missing. At this regard, the present study investigated, for the first time, the effects of Black Soldier Fly based diets (25 and 50% fish meal substitution) administration for a six months period in zebrafish (Danio rerio), from larvae to adults. A multidisciplinary approach, including biometric, biochemical, histological, spectroscopic and molecular analyses was applied. Aside a general reduction in fish growth and lipid steatosis, six-months feeding on Black Soldier Fly based diets did not show major negative effects on zebrafish. Gut histological analysis on intestine samples did not show signs of inflammation and both stress markers and immune response markers did not show significant differences among the experimental groups.

Indexed as

DietAnimalsFatty AcidsImage Processing, Computer-AssistedRNA, MessengerSimuliidaeSpectroscopy, Fourier Transform InfraredSurvival AnalysisZebrafishFatty AcidsRNA, Messenger

Identifiers

PMID31197206
PMCPMC6565691
OpenAlexW2951686677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.