Evidence map›Paper›PMID 31197180›Full record

ArticleScientific reports2019

The ion channels and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma.

Alberto Magi, Marika Masselli, Cesare Sala, Angela Guerriero, Pasquale Laise, Benedetta Puccini, Luigi Rigacci, Carla Breschi, Olivia Crociani, Serena Pillozzi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  8. IKCell death & disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Alberto MagiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Marika MasselliDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Cesare SalaDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Angela GuerrieroDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Pasquale LaiseDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Benedetta PucciniHematology Department, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy.
Luigi RigacciHematology Department, Azienda Ospedaliero Universitaria Careggi AOUC, Florence, Italy.
Carla BreschiHemato-oncology unit, Ospedale San Jacopo, Pistoia, Italy.
Olivia CrocianiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Serena PillozziDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Annarosa ArcangeliDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy. annarosa.arcangeli@unifi.it.ORCID http://orcid.org/0000-0002-6317-9648
University of Florence · ITAzienda Ospedaliero-Universitaria Careggi · ITOspedale del Ceppo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The definition of the gene expression profile of genes encoding Ion Channels and Transporters (ICT-GEP) represents a novel and attracting aspect in cancer. We determined the ICT-GEP of Follicular Lymphoma (FL), and compared it with that of the more aggressive Diffuse Large B Cell Lymphoma (DLBCL). cDNA microarray data were collected both from patients enrolled for this study, and from public datasets. In FL the ICT-GEP indicated the overexpression of both the K

Indexed as

Disease ProgressionGene Expression ProfilingGene Expression Regulation, NeoplasticAgedCohort StudiesDatabases, GeneticFemaleGene Regulatory NetworksHumansIon ChannelsLymphoma, FollicularLymphoma, Large B-Cell, DiffuseMaleMembrane Transport ProteinsMiddle AgedIon ChannelsMembrane Transport Proteins

Identifiers

PMID31197180
PMCPMC6565741
OpenAlexW2949321253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.