ArticleCell death & disease2019
Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth.
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Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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54citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
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Who cites it
54 citing papers in PubMed, 95 citations in OpenAlex.
- Mitochondrial Complex V Dysfunction in Neurodegeneration: Secondary Bystander or Primary Driver?Brain sciences · 2026Review
- Postmortem energy metabolism and meat quality development: Advances in basic pathways, endogenous regulatory factors, and exogenous management strategies.Journal of advanced research · 2026Review
- Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson's disease.iScience · 2026Article
- Reversing Mitochondrial Dysfunction in Optineurin E50K Glaucoma: A Metabolic Approach to Neuroprotection.Research square · 2026Article
- UQCRC1 deficiency impairs mitophagy via PINK1-dependent mechanisms in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Bridging the gap in Parkinson's disease research: from general pathophysiology to advanced 3d cell culture models.Cell communication and signaling : CCS · 2025Review
- CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.Science advances · 2025Article
- Cryo-EM structure of the brine shrimp mitochondrial ATP synthase suggests an inactivation mechanism for the ATP synthase leak channel.Cell death and differentiation · 2025Article
- Reduced DJ-1-F1Fo ATP synthase association correlates with midbrain dopaminergic neuron vulnerability in idiopathic Parkinson's disease.Science advances · 2025Article
- DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction.bioRxiv : the preprint server for biology · 2025Article
- The Mitochondrial Foundations of Parkinson's Disease: Therapeutic Implications.Aging and disease · 2025Review
- Redox modulatory role of DJ-1 in Parkinson's disease.Biogerontology · 2025Review
- Ferroptosis: mechanisms and therapeutic targets.MedComm · 2024Review
- Mitochondrial Aconitase and Its Contribution to the Pathogenesis of Neurodegenerative Diseases.International journal of molecular sciences · 2024Review
- Protein modification in neurodegenerative diseases.MedComm · 2024Review
- Mitochondrial protective potential of fucoxanthin in brain disorders.Journal of nutritional science · 2024Review
- Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- O-GlcNAcylation is essential for therapeutic mitochondrial transplantation.Communications medicine · 2023Article
- Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus.Developmental cell · 2023Article
- IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential.Communications biology · 2023Article
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 5 countries.
Rongmin ChenDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Han-A ParkDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Nelli MnatsakanyanDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Yulong NiuDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Pawel LicznerskiDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Jing WuDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Paige MirandaDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Morven GrahamDepartment of Cell Biology, Yale University, New Haven, CT, USA.
Jack TangDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
Agnita J W BoonDepartment of Neurology, Erasmus MC, Rotterdam, The Netherlands.
Giovanni CossuNeurology Service and Stroke Unit, Brotzu General Hospital, Cagliari, Italy.
Wim MandemakersDepartment of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Vincenzo BonifatiDepartment of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Peter J S SmithInstitute of Life Sciences, University of Southampton, Southampton, England.ORCID http://orcid.org/0000-0003-4400-6853
Kambiz N AlavianMarine Biological Laboratory, Woods Hole, MA, USA.
Elizabeth A JonasDepartment of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA. elizabeth.jonas@yale.edu.
Yale University · USErasmus MC · NLMarine Biological Laboratory · USAzienda Ospedaliera G. Brotzu · ITUniversity of Alabama · US
Funding
Mitochondrial Ion Channels in Hypoxic NeuronsR37NS045876 · NINDS · YALE UNIVERSITY · PI Elizabeth Ann Jonas · 2014 to 2026
$4.9MMitochondrial control of protein translation in Fragile XR01NS112706 · NINDS · YALE UNIVERSITY · PI Elizabeth Ann Jonas, Pawel Licznerski · 2019 to 2026
$3.6MRole of DJ1 in mitochondrial biogenergetics and neuronal metabolismR01NS081746 · NINDS · YALE UNIVERSITY · PI JONAS, ELIZABETH ANN · 2014 to 2018
$2.2MMolecular components of the mitochondrial permeability transition pore and its role in neurodegenerative diseasesK01AG054734 · NIA · YALE UNIVERSITY · PI MNATSAKANYAN, NELLI · 2017 to 2021
$639kNIA NIH HHS K01 AG054734NINDS NIH HHS R01 NS081746NINDS NIH HHS R01 NS112706NINDS NIH HHS R37 NS045876
Abstract
Familial Parkinson's disease (PD) protein DJ-1 mutations are linked to early onset PD. We have found that DJ-1 binds directly to the F
Indexed as
AnimalsDopaminergic NeuronsGene ExpressionHumansMembrane Potential, MitochondrialMiceMice, Inbred C57BLMice, KnockoutMitochondriaMitochondrial MembranesMitochondrial Proton-Translocating ATPasesProtein BindingProtein Deglycase DJ-1Rats, Sprague-DawleyATP5F1B protein, humanMitochondrial Proton-Translocating ATPasesPARK7 protein, humanProtein Deglycase DJ-1
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.