Evidence map›Paper›PMID 31196985›Full record

ArticleScience (New York, N.Y.)2019

A microbial factory for defensive kahalalides in a tripartite marine symbiosis.

Jindong Zan, Zhiyuan Li, Ma Diarey Tianero, Jeanette Davis, Russell T Hill, Mohamed S Donia

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 113 citations in OpenAlex.

  1. Biosynthetic origin of anticancer dolastatin 15 reveals a noncanonical NRPS architecture enabling 2-keto acid activation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  20. Exploring Sound Frequency Detection in the Golden Rabbitfish,Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jindong ZanDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-9238-9054
Zhiyuan LiPrinceton Center for Theoretical Science, Princeton University, Princeton, NJ 08544, USA.
Ma Diarey TianeroDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0001-8699-252X
Jeanette DavisInstitute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202, USA.
Russell T HillInstitute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202, USA.
Mohamed S DoniaDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. donia@princeton.edu.ORCID 0000-0002-9604-2912
Princeton University · USUniversity of Maryland, Baltimore · US

Funding

Uncultivated bacterial symbionts of humans: an untapped resource for drug discoveryDP2AI124441 · NIAID · PRINCETON UNIVERSITY · PI ABOU DONIA, MOHAMED · 2015 to 2015
$2.4M
NIAID NIH HHS DP2 AI124441
6 · The paper itself

Abstract

Chemical defense against predators is widespread in natural ecosystems. Occasionally, taxonomically distant organisms share the same defense chemical. Here, we describe an unusual tripartite marine symbiosis, in which an intracellular bacterial symbiont ("

Indexed as

ChlorophytaGastropodaPredatory BehaviorSymbiosisAnimalsBiological EvolutionFlavobacteriaceaeGlycosidesTriterpenesGlycosidesTriterpenes

Identifiers

PMID31196985
PMCPMC12168154
OpenAlexW2950608592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.