Evidence map›Paper›PMID 31196964›Full record

SynthesisBioscience reports2019

Diagnostic value of RASSF1A methylation for breast cancer: a meta-analysis.

Mingyi Li, Chunpeng Wang, Binbin Yu, Xueyuan Zhang, Fang Shi, Xin Liu

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

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  10. Simultaneously Both Expression ofBalkan journal of medical genetics : BJMG · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mingyi LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China.
Chunpeng WangSchool of Mathematics and Statistics, Northeast Normal University, Changchun 130000, Jilin, China.
Binbin YuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China.
Xueyuan ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China.
Fang ShiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China.
Xin LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China liuxinjlu01@163.com.ORCID 0000-0002-3486-5753
Jilin University · CNNortheast Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous studies reported that RAS-association domain family 1 isoform A (

methodsSuch databases as PubMed, Cochrane Library and Web of Science databases were searched for literatures until May 2019. A meta-analysis was performed utilizing STATA and Revman softwares. Furthermore, subgroup analysis was adopted to determine likely sources of heterogeneity.

resultsTotally 19 literatures with 1849 patients and 1542 controls were included in the present study. Sensitivity, specificity, diagnostic odds ratio (DOR) and the area under the summary receiver operating characteristic curve (AUC) of

conclusions

Indexed as

Biomarkers, TumorBreast NeoplasmsDNA MethylationFemaleHumansROC CurveTumor Suppressor ProteinsBiomarkers, TumorRASSF1 protein, humanTumor Suppressor Proteinsbreast cancerdiagnosisDNA methylationmeta-analysisRASSF1A

Identifiers

PMID31196964
PMCPMC6597854
OpenAlexW2950471723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.