Evidence map›Paper›PMID 31196949›Full record

ArticleThe European respiratory journal2019

Educational and health outcomes of children treated for asthma: Scotland-wide record linkage study of 683 716 children.

Michael Fleming, Catherine A Fitton, Markus F C Steiner, James S McLay, David Clark, Albert King, Daniel F Mackay, Jill P Pell

Open access · hybridAbstract read
In one paragraph

Article in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  9. Psychological wellbeing among parents of a child living with a serious chronic illness: A cross-sectional survey study.Journal of child health care : for professionals working with children in the hospital and community · 2025
    Article
  10. Article
  11. Article
  12. The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025
    Review
  13. Sex differences in sociodemographic, clinical, and laboratory variables in childhood asthma: A birth cohort study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Michael FlemingInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK michael.fleming@glasgow.ac.uk.ORCID 0000-0002-2185-4502
Catherine A FittonDept of Child Health, University of Aberdeen, Aberdeen, UK.
Markus F C SteinerDept of Child Health, University of Aberdeen, Aberdeen, UK.
James S McLayDept of Child Health, University of Aberdeen, Aberdeen, UK.
David ClarkInformation Services Division, National Services Scotland, NHS Scotland, Edinburgh, UK.
Albert KingScotXed, Scottish Government, Edinburgh, UK.
Daniel F MackayInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Jill P PellInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
University of Aberdeen · GBUniversity of Glasgow · GBNational Health Service Scotland · GBScottish Government · GB

Funding

Medical Research Council MR/S003800/1Wellcome Trust
6 · The paper itself

Abstract

backgroundThe global prevalence of childhood asthma is increasing. The condition impacts physical and psychosocial morbidity; therefore, wide-ranging effects on health and education outcomes are plausible.

methodsLinkage of eight Scotland-wide databases, covering dispensed prescriptions, hospital admissions, maternity records, death certificates, annual pupil census, examinations, school absences/exclusions and unemployment, provided data on 683 716 children attending Scottish schools between 2009 and 2013. We compared schoolchildren on medication for asthma with peers, adjusting for sociodemographic, maternity and comorbidity confounders, and explored effect modifiers and mediators.

resultsThe 45 900 (6.0%) children treated for asthma had an increased risk of hospitalisation, particularly within the first year of treatment (incidence rate ratio 1.98, 95% CI 1.93-2.04), and increased mortality (HR 1.77, 95% CI 1.30-2.40). They were more likely to have special educational need for mental (OR 1.76, 95% CI 1.49-2.08) and physical (OR 2.76, 95% CI 2.57-2.95) health reasons, and performed worse in school exams (OR 1.11, 95% CI 1.06-1.16). Higher absenteeism (incidence rate ratio 1.25, 95% CI 1.24-1.26) partially explained their poorer attainment.

conclusionsChildren with treated asthma have poorer education and health outcomes than their peers. Educational interventions that mitigate the adverse effects of absenteeism should be considered.

Indexed as

AbsenteeismAdolescentAdultAnti-Asthmatic AgentsAsthmaChildDatabases, FactualDrug PrescriptionsEducational StatusFemaleHospitalizationHumansLogistic ModelsMaleMedical Record LinkagePregnancyAnti-Asthmatic Agents

Identifiers

PMID31196949
PMCPMC6727030
OpenAlexW2952271547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.