Evidence map›Paper›PMID 31196892›Full record

ArticleCold Spring Harbor molecular case studies2019

Neonatal diabetes mellitus due to a novel variant in the

Sarah E Laurenzano, Cory McFall, Linda Nguyen, Dipal Savla, Nicole G Coufal, Meredith S Wright, Mari Tokita, David Dimmock, Stephen F Kingsmore, Ron S Newfield

Registry-linked trialOpen access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02917460 (Genomic Biorepository), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02917460 narecruitingnot on this map

Genomic Biorepository: Protocol for the Collection, Storage, Analysis, and Distribution of Biological Samples, Genomic and Clinical Data

TypeinterventionalSponsorRady Pediatric Genomics & Systems Medicine InstituteRan2016 to 2050Enrolled102,000ConditionsGenetic DiseasesArmsGenomic sequencing and molecular diagnostic results, if any
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Computational Analysis of Deleterious nsSNPs inJournal of personalized medicine · 2024
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sarah E LaurenzanoDivision of Pediatric Endocrinology, Department of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
Cory McFallDivision of Pediatric Intensive Care Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
Linda NguyenDepartment of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
Dipal SavlaDepartment of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
Nicole G CoufalDivision of Pediatric Intensive Care Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
Meredith S WrightRady Children's Institute for Genomic Medicine, San Diego, California 92123, USA.
Mari TokitaRady Children's Institute for Genomic Medicine, San Diego, California 92123, USA.
David DimmockRady Children's Institute for Genomic Medicine, San Diego, California 92123, USA.
Stephen F KingsmoreRady Children's Institute for Genomic Medicine, San Diego, California 92123, USA.
Ron S NewfieldDivision of Pediatric Endocrinology, Department of Pediatrics, University of California, San Diego, La Jolla, California 92093, USA.
University of California, San Diego · USChildren’s Institute · US

Funding

ConProject-001U19HD077693 · NICHD · RADY PEDIATRIC GENOMICS & SYSTEMS MEDICINE INSTITUTE · PI KINGSMORE, STEPHEN FRANCIS · 2013 to 2018
$6.2M
NICHD NIH HHS U19 HD077693
6 · The paper itself

Abstract

Neonatal diabetes mellitus (NDM) is a rare condition that presents with diabetes in the first few months of life. The treatment of NDM may differ depending on the genetic etiology, with numerous studies showing the benefit of sulfonylurea therapy in cases caused by mutations in

Indexed as

Diabetes MellitusDiabetic KetoacidosisFemaleHumansInfant, NewbornInfant, Newborn, DiseasesInsulinMutationInsulindiabetes mellitusdiabetic ketoacidosis

Identifiers

PMID31196892
PMCPMC6672029
OpenAlexW2949254712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.