Evidence map›Paper›PMID 31196872›Full record

ArticleLife science alliance2019

Evidence for vesicle-mediated antigen export by the human pathogen

Jose Thekkiniath, Nicole Kilian, Lauren Lawres, Meital A Gewirtz, Morven M Graham, Xinran Liu, Michel Ledizet, Choukri Ben Mamoun

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Acquired motility ofProceedings of the National Academy of Sciences of the United States of America · 2026
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  8. A set of diagnostic tests for detection of active Babesia duncani infection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
    Article
  9. Identification ofInfection and immunity · 2024
    Article
  10. ContinuousInfection and immunity · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Major Surface Antigens in ZoonoticPathogens (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Pathogens (Basel, Switzerland) · 2021
    Article
  20. Plasmepsin-like Aspartyl Proteases inPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jose ThekkiniathDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Nicole KilianDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Lauren LawresDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.
Meital A GewirtzDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-8033-6107
Morven M GrahamCenter for Cellular and Molecular Imaging Electron Microscopy Core Facility, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-4375-3198
Xinran LiuDepartment of Cell Biology, Yale School of Medicine, New Haven, CT, USA.
Michel LedizetL2 Diagnostics, Limited Liability Corporation, New Haven, CT, USA.
Choukri Ben MamounDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA choukri.benmamoun@yale.edu.ORCID 0000-0001-5028-1400
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Development of endochin-like quinolones for babesiosis therapyR01AI123321 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI · 2017 to 2020
$2.7M
A super-resolution microscope for research and educationS10OD020142 · OD · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2015 to 2015
$600k
An antigen-detection assay to diagnose Babesia microti infectionR43AI136118 · NIAID · L2 DIAGNOSTICS, LLC · PI LEDIZET, MICHEL · 2018 to 2018
$300k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI123321NIAID NIH HHS R43 AI136118NIH HHS S10 OD020142
6 · The paper itself

Abstract

The apicomplexan parasite

Indexed as

AnimalsAntigens, ProtozoanBabesia microtiBabesiosisBiological TransportDisease Models, AnimalErythrocytesHumansImmunodominant EpitopesMiceMice, KnockoutTransport VesiclesAntigens, ProtozoanImmunodominant Epitopes

Identifiers

PMID31196872
PMCPMC6572159
OpenAlexW2952677605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.