Evidence map›Paper›PMID 31196859›Full record

ArticleAJNR. American journal of neuroradiology2019

Quantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient Population.

B B Reynolds, S By, Q R Weinberg, A A Witt, A T Newton, H R Feiler, B Ramkorun, D B Clayton, P Couture, J E Martus and 4 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Mapping Pediatric Spinal Cord Development with Age.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

B B ReynoldsInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0001-9196-1461
S ByInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0001-8158-2732
Q R WeinbergInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0002-4284-8400
A A WittInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0002-2939-263X
A T NewtonFrom the Department of Radiology and Radiological Sciences (A.T.N., P.C., S.A.S., A.B.).ORCID 0000-0001-6539-8783
H R FeilerInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0002-1097-8964
B RamkorunInstitute of Imaging Science (B.B.R., S.B., Q.R.W., A.A.W., A.T.N., H.R.F., B.R., S.A.S., A.B.), Vanderbilt University, Nashville, Tennessee.ORCID 0000-0001-9678-4118
D B ClaytonUrology (D.B.C., M.A.).ORCID 0000-0003-4460-4167
P CoutureFrom the Department of Radiology and Radiological Sciences (A.T.N., P.C., S.A.S., A.B.).ORCID 0000-0002-7347-5002
J E MartusDivision of Pediatric Orthopaedics (J.E.M.), Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.ORCID 0000-0002-5768-6715
M AdamsUrology (D.B.C., M.A.).ORCID 0000-0003-1043-9458
J C WellonsFrom the Department of Radiology and Radiological Sciences (A.T.N., P.C., S.A.S., A.B.).ORCID 0000-0002-5418-4672
S A SmithFrom the Department of Radiology and Radiological Sciences (A.T.N., P.C., S.A.S., A.B.).ORCID 0000-0002-4168-562X
A BhatiaFrom the Department of Radiology and Radiological Sciences (A.T.N., P.C., S.A.S., A.B.) aashimbhatia@gmail.com.ORCID 0000-0002-3702-9304

Funding

Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
Structural and Functional MRI of the Cervical Spinal Cord in Multiple SclerosisR01NS109114 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SMITH, SETH A · 2018 to 2022
$1.7M
Mechanisms of Cellular Adaptation in CystitisK08DK106472 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAYTON, DOUGLASS BROOKS · 2015 to 2019
$713k
NIBIB NIH HHS T32 EB001628NIDDK NIH HHS K08 DK106472NINDS NIH HHS R01 NS109114
6 · The paper itself

Abstract

background and purposeThe purpose of the study is to characterize diffusion tensor imaging indices in the developing spinal cord, evaluating differences based on age and cord region. Describing the progression of DTI indices in the pediatric cord increases our understanding of spinal cord development. MATERIALS AND

methodsA retrospective analysis was performed on DTI acquired in 121 pediatric patients (mean, 8.6 years; range, 0.3-18.0 years) at Monroe Carell Jr. Children's Hospital at Vanderbilt from 2017 to 2018. Diffusion-weighted images (15 directions;

resultsAnalyses of covariance revealed significant correlations of age with axial diffusivity, mean diffusivity, and fractional anisotropy (all,

conclusionsThis research demonstrates that diffusion evolves in the pediatric spinal cord during development, dependent on both cord region and the diffusion index of interest. Future research could investigate how diffusion may be affected by common pediatric spinal pathologies.

Indexed as

NeurogenesisAdolescentAlgorithmsAnisotropyChildChild, PreschoolDiffusion Tensor ImagingFemaleHumansImage Processing, Computer-AssistedInfantMaleNeuroimagingRetrospective StudiesSpinal Cord

Identifiers

PMID31196859
PMCPMC7048550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.