Evidence map›Paper›PMID 31196216›Full record

ArticleJournal of cardiothoracic surgery2019

Mitral valve repair: moving towards a personalized ring.

Antonios Pitsis, Timotheos Kelpis, Efstratios Theofilogiannakos, Nikolaos Tsotsolis, Harisios Boudoulas, Konstantinos Dean Boudoulas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Antonios PitsisDepartment of Cardiac Surgery, St. Luke's Hospital, Thessaloniki, Greece. apitsis@otenet.gr.ORCID http://orcid.org/0000-0001-5745-7886
Timotheos KelpisDepartment of Cardiac Surgery, St. Luke's Hospital, Thessaloniki, Greece.
Efstratios TheofilogiannakosDepartment of Cardiac Surgery, St. Luke's Hospital, Thessaloniki, Greece.
Nikolaos TsotsolisDepartment of Cardiac Surgery, St. Luke's Hospital, Thessaloniki, Greece.
Harisios BoudoulasDepartment of Medicine, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA.
Konstantinos Dean BoudoulasDepartment of Medicine, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA.
St. Luke's Hospital · GRThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral valve repair with the use of an annuloplasty ring is the procedure of choice in patients with significant mitral regurgitation (MR) due to floppy mitral valve (FMV)/mitral valve prolapse (MVP). The mitral annular size, shape and motion may vary substantially among patients and thus, commercially available rings may not be suitable for each individual patient.

methodsA "personalized ring" (PR) was easily constructed in the operating room using a Dacron sheet and titanium ligating clips to custom fit to each individual mitral annulus shape and size. There were 127 patients with severe MR due to FMV/MVP that underwent mitral valve repair surgery; 58 patients received a PR and 69 patients received a commercial Carpentier-Edwards Physio II ring. The patient records were retrospectively analysed.

resultsThere were no surgical deaths. In-hospital length-of-stay and blood transfusions were not statistically different between the two groups. Mitral valve area was greater (p < 0.05) in the PR group (3.78 ± 0.22) compared to the Physio II ring group (3.13 ± 0.21). Mitral annular area changed from systole to diastole by 14.35% ± 3.28% in the PR group and did not change in the Physio II ring group (p < 0.05). Systolic anterior motion (SAM) of the mitral valve occurred in 2 patients with the Physio II ring and no patients with the PR. Up to 8 years follow-up, all patients in both groups were alive with NYHA functional class I-II symptoms and mild or less MR.

conclusionsThe PR is suitable for all patients with significant MR due to FMV/MVP who require MV repair. The precise fit of the PR to the mitral annulus better preserves valve area and sphincter function of the mitral annulus, prevents SAM and provides excellent short and long-term results.

Indexed as

Heart Valve ProsthesisProsthesis DesignAdultAgedBlood Loss, SurgicalBlood TransfusionFemaleHeart Valve Prosthesis ImplantationHumansLength of StayMaleMiddle AgedMitral Valve InsufficiencyMitral Valve ProlapseRetrospective StudiesSystoleFloppy mitral valveMitral regurgitationMitral valve prolapsePersonalized ringRepair

Identifiers

PMID31196216
PMCPMC6567592
OpenAlexW2951781369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.