ArticleRadiation oncology (London, England)2019
Comparison of treatment plans between IMRT with MR-linac and VMAT for lung SABR.
Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Clinical application of MR-Linac in tumor radiotherapy: a systematic review.Radiation oncology (London, England) · 2023Pooled it
- Performance evaluation of a visual guidance patient-controlled respiratory gating system for respiratory-gated magnetic-resonance image-guided radiation therapy.Physical and engineering sciences in medicine · 2022Trial
- A hybrid IGRT workflow using SGRT and CBCT for prostate SBRT: Feasibility, efficiency, and safety.Journal of applied clinical medical physics · 2025Article
- Deep Learning-Based Cardiac Chamber Segmentation in Magnetic Resonance-Guided Adaptive Radiation Therapy.Advances in radiation oncology · 2025Article
- Effects of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) on survival benefits and poor prognostic factors in patients with cervical cancer.Biomedical engineering online · 2025Article
- Real-time magnetic resonance imaging guided accelerator in stereotactic body radiation therapy for non-small cell lung cancer.Journal of thoracic disease · 2025Article
- Assessing population-based to personalized planning strategies for head and neck adaptive radiotherapy.Journal of applied clinical medical physics · 2025Article
- Comparative analysis of delivered and planned doses in target volumes for lung stereotactic ablative radiotherapy.Radiation oncology (London, England) · 2024Article
- Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells.International journal of molecular sciences · 2023Article
- Non-Oncological Radiotherapy: A Review of Modern Approaches.Journal of personalized medicine · 2022Review
- Compact bunker shielding assessment for 1.5 T MR-Linac.Scientific reports · 2022Article
- Article
- Recognising the challenges of implementing multi-centre adaptive plan of the day radiotherapy.Technical innovations & patient support in radiation oncology · 2022Article
- Patient positioning and immobilization procedures for hybrid MR-Linac systems.Radiation oncology (London, England) · 2021Review
- Can reducing planning safety margins broaden the inclusion criteria for lung stereotactic ablative body radiotherapy?Journal of medical radiation sciences · 2021Article
- Dosimetric comparison of MR-linac-based IMRT and conventional VMAT treatment plans for prostate cancer.Radiation oncology (London, England) · 2021Article
- MRI-Guided Radiation Therapy.Advances in oncology · 2021Article
- MR-Linac Radiotherapy - The Beam Angle Selection Problem.Frontiers in oncology · 2021Article
- Adaptive MR-Guided Stereotactic Radiotherapy is Beneficial for Ablative Treatment of Lung Tumors in High-Risk Locations.Frontiers in oncology · 2021Article
- The quantification and potential impact of dark current on treatments with an MR-guided radiotherapy (MRgRT) system.Journal of applied clinical medical physics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe aim of this study was to compare the plan quality of magnetic-resonance image-based intensity modulated radiation therapy (MRI-based-IMRT) with the MRIdian Linac system to that of volumetric modulated arc therapy (VMAT) with the TrueBeam STx system for lung stereotactic ablative radiotherapy (SABR).
methodsA total of 22 patients with tumors located in the lower lobe were retrospectively selected for the study. For each patient, both the MRI-based-IMRT and VMAT plans were generated using an identical CT image set and identical structures with the exception of the planning target volume (PTV). The PTVs of the MRI-based-IMRT were generated by adding an isotropic margin of 3 mm from the gross tumor volume, whereas those of VMAT were generated by adding an isotropic margin of 5 mm from the internal target volume. For both the MRI-based-IMRT and VMAT, the prescription doses to the PTVs were 60 Gy in four fractions.
resultsThe average PTV volume of the MRI-based-IMRT was approximately 4-times smaller than that of VMAT (p < 0.001). The maximum dose to the bronchi for the MRI-based-IMRT was smaller than that for the VMAT (20.4 Gy versus 24.2 Gy, p < 0.001). In addition, V
conclusionsThe MRI-based-IMRT using the MRIdian Linac system could reduce doses to bronchi, rib, ipsilateral lung, and whole body compared to VMAT for lung SABR when the tumor was located in the lower lobe.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.