ArticleBMC public health2019
Waist circumference trajectories and risk of type 2 diabetes mellitus in Korean population: the Korean genome and epidemiology study (KoGES).
Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 47 citations in OpenAlex.
- Association between trajectories of waist circumference with incidence of type 2 diabetes mellitus, Tehran lipid and glucose study.Scientific reports · 2026Article
- Waist circumference and grip strength and their joint relations to type 2 diabetes incidence in UK Biobank.BMC medicine · 2026Article
- Long-term waist circumference and diabetes risk in premenopausal women: role of shared risk factors.BMC women's health · 2025Article
- Life-long body mass index trajectories and cardiometabolic biomarkers-the Danish diet, cancer, and health-next generations cohort.International journal of obesity (2005) · 2025Article
- Artificial intelligence survival models for identifying relevant risk factors for incident diabetes in Azar cohort population.Health promotion perspectives · 2025Article
- Body composition markers are more strongly associated with type 2 diabetes than inflammatory markers-Results from the study of health in Pomerania.European journal of clinical investigation · 2025Article
- The 14-year cumulative genetic high blood pressure and risk of type 2 diabetes in Korean: observational and Mendelian randomization evidence.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Observational
- Do Time-Dependent Repeated Measures of Anthropometric and Body Composition Indices Improve the Prediction of Incident Diabetes in the Cohort Study? Findings from a Community-Based Korean Genome and Epidemiology Study.Diabetes & metabolism journal · 2025Article
- Factors affecting the survival of prediabetic patients: comparison of Cox proportional hazards model and random survival forest method.BMC medical informatics and decision making · 2024Article
- Association of Life's Essential 8 with all-cause mortality and risk of cancer: a prospective cohort study.BMC public health · 2024Article
- Remnant cholesterol trajectory and subclinical arteriosclerosis: a 10-year longitudinal study of Chinese adults.Scientific reports · 2024Article
- Association of a High Healthy Eating Index Diet with Long-Term Visceral Fat Loss in a Large Longitudinal Study.Nutrients · 2024Article
- Article
- Advancing diabetes prediction with a progressive self-transfer learning framework for discrete time series data.Scientific reports · 2023Article
- Association between DIO2 Thr92Ala polymorphism and hypertension in patients with hypothyroidism: Korean Genome and Epidemiology Study.The Korean journal of internal medicine · 2023Article
- Maternal obesity and programming of metabolic syndrome in the offspring: searching for mechanisms in the adipocyte progenitor pool.BMC medicine · 2023Review
- Physical activity, sedentary behavior, and cardiovascular disease risk in Korea: a trajectory analysis.Epidemiology and health · 2023Article
- Association between long-term weight-change trajectory and cardiovascular disease risk by physical activity level.Scientific reports · 2022Article
- Article
- Prevalence of overweight and obesity amongst patients with diabetes and their non-diabetic family members in Senwabarwana, Limpopo province, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
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3 authors at 1 institution in 1 country.
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Abstract
backgroundTo classify waist circumference (WC) trajectories and examine each trajectory's association with risk of incident type 2 diabetes mellitus (T2DM).
methodsIn Korean Genome and Epidemiology Study (KoGES 2001-2014), 4992 participants aged 40 years and above who received biennial health examinations from wave 1 to wave 4 (2001-2008) were selected. Five distinct trajectory groups were identified for WC using group-based trajectory modeling methods such as censored normal model. Cox proportional hazards model was used to examine the association of trajectories with risk of T2DM.
resultsDuring 31,118 person-years of follow-up (mean follow-up duration, 6.2 years), 276 incident cases of T2DM were identified. Through trajectory analysis, 5 distinct WC patterns were found during wave1 to wave 4, which were "Group A" was stable on very low levels, "Group B" was stable on low levels, "Group C" was stable on moderate levels, "Group D" had increasing pattern on elevated levels, "Group E" was shown increasing on high levels. Age-standardized incidences rates per 100,000 person-years were increased with WC expanding trajectory group (193.9 for Group A, 498.4 for Group B, 661.9 for Group C, 1845.9 for Group D, and 2045.0 for Group E). In multivariate analysis after adjusting for confounding variable at wave 4, Group B (Hazard ratio (HR), 2.2; 95% confidence interval (CI), and 1.1-4.6), Group C (HR: 2.5, 95% CI: 1.2-5.0), Group D (HR: 5.4, 95% CI: 2.7-10.9), Group E (HR: 7.3, 95% CI: 3.5-15.4) had a higher risk of T2DM than Group A. After further adjusting for body mass index strongly correlated with WC, the association was attenuated.
conclusionsWC trajectory was a significant predictor of T2DM risk in increasing trajectories on high level. This finding indicate the importance of WC management across prolong lifespan by assessing the prognosis and prevention strategies of high-risk populations for T2DM in middle-aged adults.
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