SynthesisBMC infectious diseases2019
Hepatitis E virus infection among pregnant women in Africa: systematic review and meta-analysis.
Synthesis in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- A systematic review of the epidemiology of Hepatitis E virus infection in South - Eastern Asia.Virulence · 2021Pooled it
- Molecular and serological evidence of hepatitis E virus genotype 3 circulation in pigs in Senegal.One health (Amsterdam, Netherlands) · 2026Article
- Hepatitis E virus seroprevalence in South Africa: a multi-site study among HIV-negative and HIV-positive adults and age-stratified children (2-17 Years).BMC infectious diseases · 2026Article
- Prevalence of Hepatitis E Virus Infection Among Pregnant Women in Tunisia: Findings from a Large Cohort Study.Pathogens (Basel, Switzerland) · 2026Article
- Current global estimates, risk factors, and knowledge gaps for Hepatitis E virus (HEV): A scoping review.PLoS neglected tropical diseases · 2026Article
- Hepatitis E Virus in the Role of an Emerging Food-Borne Pathogen.Microorganisms · 2025Review
- Seroprevalence patterns of viral hepatitis B, C, and E among internally displaced persons in Borno State, Nigeria.IJID regions · 2024Article
- Systematic Evaluation of Guidelines for the Diagnosis and Treatment of Hepatitis E Virus Infection.Journal of clinical and translational hepatology · 2024Review
- The burden of hepatitis E virus infection among Ghanaian pregnant women.Frontiers in public health · 2024Article
- Diagnostic Approach to Elevated Liver Function Tests during Pregnancy: A Pragmatic Narrative Review.Journal of personalized medicine · 2023Article
- Epidemiology of Hepatitis E.Advances in experimental medicine and biology · 2023Article
- Low seroprevalence of hepatitis E virus in pregnant women in an urban area near Pretoria, South Africa.IJID regions · 2022Article
- Hepatitis E, Schistosomiasis and Echinococcosis-Prevalence in a Cohort of Pregnant Migrants in Germany and Their Influence on Fetal Growth Restriction.Pathogens (Basel, Switzerland) · 2022Article
- Seroprevalence and burden of hepatitis E viral infection among pregnant women in central Nigeria attending antenatal clinic at a Federal Medical Centre in Central Nigeria.Frontiers in medicine · 2022Article
- First molecular detection of hepatitis E virus genome in camel and pig faecal samples in Ethiopia.Virology journal · 2021Article
- Prevalence and clinical correlation of hepatitis E virus antibody in the patients' serum samples from a tertiary care hospital in Thailand during 2015-2018.Virology journal · 2021Article
- Viral hepatitis and pregnancy.Nature reviews. Gastroenterology & hepatology · 2021Review
- The Vaginal Virome-Balancing Female Genital Tract Bacteriome, Mucosal Immunity, and Sexual and Reproductive Health Outcomes?Viruses · 2020Review
- Seroprevalence of Dromedary Camel HEV in Domestic and Imported Camels from Saudi Arabia.Viruses · 2020Article
- Innate Immune Responses to Acute Viral Infection During Pregnancy.Frontiers in immunology · 2020Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere have been a number of studies about seroprevalence of HEV among pregnant women in Africa. However, the finding of seroprevalence of HEV infection among pregnant women is variable and inconsistent. Therefore; this systematic review intended to provide the pooled seroprevalence of HEV among pregnant women in Africa.
methodsWe searched, Pub Med, Science direct, African online journals and Google scholar electronic data bases and all available references until August 30, 2018. We included cross sectional studies and cohort studies. The search was further limited studies done in African pregnant women. Statistical analysis done by using Stata (version 11) software. The overall pooled prevalence of HEV presented by using the forest plot with 95% CI. The methodological qualities of included studies were assessed using Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instruments.
resultThe pooled seroprevalence of HEV among pregnant women in Africa was 29.13% (95% CI 14.63-43.63). The highest seroprevalence was 84.3% in Egypt and the lowest 6.6% reported in Gabon. There was highest heterogeneity level where I
conclusionThe seroprevalence of HEV among pregnant women in Africa is high. The seroprevalence of HEV among pregnant women differ with geographic location and assay method. Therefore, it is recommended to conduct further research on commercial ELISA kit sensitivity and specificity, molecular tests, incidence, morbidity and mortality and vertical transmission of HEV from mother to infant in Africa.
trial registrationCRD42018084963 .
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