Evidence map›Paper›PMID 31195936›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography.

Viktoria Zoufal, Severin Mairinger, Markus Krohn, Thomas Wanek, Thomas Filip, Michael Sauberer, Johann Stanek, Claudia Kuntner, Jens Pahnke, Oliver Langer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Effect of probenecid on the whole-body disposition of 6-bromo-7-[European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. First-in-human evaluation of 6-bromo-7-[European journal of nuclear medicine and molecular imaging · 2024
    Article
  4. Advancing 6-bromo-7-[EJNMMI radiopharmacy and chemistry · 2024
    Article
  5. Review
  6. Improved synthesis of 6-bromo-7-[EJNMMI radiopharmacy and chemistry · 2024
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Viktoria ZoufalPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Severin MairingerPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Markus KrohnDepartment of Neuro/Pathology, University of Oslo (UiO) and Oslo University Hospital (OUS), Oslo, Norway.
Thomas WanekPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Thomas FilipPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Michael SaubererPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Johann StanekPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Claudia KuntnerPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.
Jens PahnkeDepartment of Neuro/Pathology, University of Oslo (UiO) and Oslo University Hospital (OUS), Oslo, Norway.
Oliver LangerPreclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria.ORCID 0000-0002-4048-5781
Austrian Institute of Technology · ATOslo University Hospital · NO

Funding

Austrian Science Fund FWF I 1609
6 · The paper itself

Abstract

Previous data suggest a possible link between multidrug resistance-associated protein 1 (ABCC1) and brain clearance of beta-amyloid (Aβ). We used PET with 6-bromo-7-[

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorAnimalsATP-Binding Cassette, Sub-Family C ProteinsDisease Models, AnimalFemaleMiceMice, Inbred C57BLMice, TransgenicNeuroimagingPositron-Emission TomographyPresenilin-1RadiopharmaceuticalsAmyloid beta-Protein PrecursorATP-Binding Cassette, Sub-Family C Proteinsmultidrug resistance-associated protein 1Presenilin-1RadiopharmaceuticalsAlzheimer’s diseaseAPP/PS1-21 miceastrocytesbeta-amyloidmultidrug resistance-associated protein 1

Identifiers

PMID31195936
PMCPMC7181082
OpenAlexW2950936925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.