ArticleTurkish journal of medical sciences2019
Evaluation of cancer risk in patients with periodontal diseases
Article in Turkish journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review.The Prostate · 2025Pooled it
- Pooled it
- Periodontal Disease and Tooth Loss Are Associated with Lung Cancer Risk.BioMed research international · 2020Pooled it
- Potential risk of certain cancers among patients with Periodontitis: a supplementary meta-analysis of a large-scale population.International journal of medical sciences · 2020Pooled it
- Periodontal disease and the risk of prostate cancer: a meta-analysis of cohort studies.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Incident Lung Cancer and Mortality: Data From Health ABC Using Periodontal Status and Tooth Loss.Oral diseases · 2026Article
- The oral - X axis: from periodontal dysbiosis to systemic disease.Frontiers in immunology · 2026Review
- The Relationship Between Periodontal Disease and Breast Cancer: From Basic Mechanism to Clinical Management and Prevention.Oral health & preventive dentistry · 2023Review
- Unraveling the impact of primary immunodeficiency disorders on the microbiota of dental caries in children through 16S rRNA gene-based metagenomic analysis.Turkish journal of medical sciences · 2023Article
- Subgingival Periopathogens Assessment and Clinical Periodontal Evaluation of Gastric Cancer Patients-A Cross Sectional Pilot Study.Pathogens (Basel, Switzerland) · 2022Article
- PD-L1 Up-Regulation in Prostate Cancer Cells byFrontiers in cellular and infection microbiology · 2022Article
- Oral Microbial Species and Virulence Factors Associated with Oral Squamous Cell Carcinoma.Microbial ecology · 2021Article
- Oral microbiota in the oral-genitourinary axis: identifying periodontitis as a potential risk of genitourinary cancers.Military Medical Research · 2021Review
- Panoramic Dental Reconstruction for Faster Detection of Dental Pathology on Medical Non-dental CT Scans: a Proof of Concept from CT Neck Soft Tissue.Journal of digital imaging · 2021Article
- A potential therapeutic strategy for prostatic disease by targeting the oral microbiome.Medicinal research reviews · 2021Review
- Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases.Journal of clinical medicine · 2021Article
- Cancer incidence in Behçet's disease.Irish journal of medical science · 2020Article
- Cellular and Biochemical Changes in Different Categories of Periodontitis: A Patient-based Study.Journal of International Society of Preventive & Community DentistryArticle
- Potential Common Molecular Mechanisms Between Periodontitis and Prostate Cancer: A Network Analysis of Differentially Expressed miRNAs.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: In this study, we aimed to assess the cancer risk among patients with periodontal disease. Materials and methods: Patients diagnosed with periodontal diseases at Hacettepe University between 2007 and 2012 were included and data on the diagnosis of any cancer after periodontal disease were collected from patient files. The age- and sex-standardized incidence rates (SIRs) were calculated using Turkish National Cancer Registry 2013 data. Results: A total of 5199 patients were included. Median follow-up was 7.2 years. Patients with periodontal diseases had 17% increased risk of cancer compared with the expected counts for the corresponding age and sex groups (SIR: 1.17; 95% CI: 1.04–1.3, P = 0.006). The increased cancer risk was statistically significant in women (SIR: 1.24; 95% CI: 1.05–1.45, P = 0.008) but not in men. Among women with periodontal disease, the risks of breast cancer (SIR: 2.19) and head and neck cancer (SIR: 4.71) were significantly increased. Among men, the risks of prostate cancer (SIR: 1.84), head and neck cancer (SIR: 3.55), and hematological cancers (SIR: 1.76) were significantly increased. Conclusion: This study showed that periodontal diseases were associated with increased risk of several cancers. Besides other well-known benefits for health, the provision of oral/dental health should be considered and employed as a cancer prevention measure.
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Registered trials
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