Evidence map›Paper›PMID 31195682›Full record

ArticleInternational journal of molecular sciences2019

A Cross-Sectional Study on 3-(2-Deoxy-β-D-Erythro-Pentafuranosyl)Pyrimido[1,2-α]Purin-10(3H)-One Deoxyguanosine Adducts among Woodworkers in Tuscany, Italy.

Filippo Cellai, Fabio Capacci, Carla Sgarrella, Carla Poli, Luciano Arena, Lorenzo Tofani, Roger W Giese, Marco Peluso

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Occupational Exposure to Dust Produced when Milling Thermally Modified Wood.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Filippo CellaiCancer Factor Risk Branch, Regional Cancer Prevention Laboratory, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy. f.cellai@ispro.toscana.it.
Fabio CapacciFunctional Unit for Prevention, Health and Safety in the Workplace, ASL10, 50139 Florence, Italy. fabio.capacci@uslcentro.toscana.it.
Carla SgarrellaFunctional Unit for Prevention, Health and Safety in the Workplace, ASL10, 50139 Florence, Italy. carla.sgarrella@uslcentro.toscana.it.
Carla PoliDepartment of Prevention, Azienda USL Toscana Centro, 50139 Florence, Italy. carla.poli@uslcentro.toscana.it.
Luciano ArenaDepartment of Prevention, Azienda USL Toscana Centro, 50139 Florence, Italy. luciano.arena@uslcentro.toscana.it.
Lorenzo TofaniDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, 50139 Florence, Italy. lorenzo120787@gmail.com.
Roger W GieseBouve College of Health Sciences, Barnett Institute, Northeastern University, Northeastern University, Boston, MA 02115, USA. r.giese@northeastern.edu.
Marco PelusoCancer Factor Risk Branch, Regional Cancer Prevention Laboratory, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy. m.peluso@ispro.toscana.it.ORCID 0000-0001-7646-7967
Azienda Usl Toscana Centro · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · ITNortheastern University · USUniversity of Florence · IT

Funding

Regione Toscana na
6 · The paper itself

Abstract

Occupational exposure to wood dust has been estimated to affect 3.6 million workers within the European Union (EU). The most serious health effect caused by wood dust is the nasal and sinonasal cancer (SNC), which has been observed predominantly among woodworkers. Free radicals produced by inflammatory reactions as a consequence of wood dust could play a major role in SNC development. Therefore, we investigated the association between wood dust and oxidative DNA damage in the cells of nasal epithelia, the target site of SNC. We have analyzed oxidative DNA damage by determining the levels of 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α]purin-10(3H)-one deoxyguanosine (M

Indexed as

Occupational ExposureWoodCross-Sectional StudiesDeoxyguanosineDinoprostDNA AdductsDustHumansItalyMaleMiddle AgedPyrimidinonesReference Standards8-epi-prostaglandin F2alphaDeoxyguanosineDinoprostDNA AdductsDustPyrimidinonesM1dGnasal epitheliaVOCswood dust

Identifiers

PMID31195682
PMCPMC6600535
OpenAlexW2948653847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.