ArticleInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2019
Associations of depression severity with heart rate and heart rate variability in young adults across normative and clinical populations.
Article in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physiological Effects of Psychological Interventions Among Persons with Financial Stress: A Systematic Review, Meta-analysis, and Introduction to Psychophysiological Economics.Applied psychophysiology and biofeedback · 2024Pooled it
- Digital phenotype of mood disorders: A conceptual and critical review.Frontiers in psychiatry · 2022Pooled it
- Functional Connectivity Within the Central Autonomic Network Increases During Resonance Paced Breathing at 0.1 Hz.Psychophysiology · 2026Article
- Tracking mood symptoms across the menstrual cycle in women with depression using ecological momentary assessment and heart rate variability.BMJ mental health · 2025Article
- Article
- Diurnal variation of cardiac autonomic activity in adolescent non-suicidal self-injury.European archives of psychiatry and clinical neuroscience · 2024Article
- Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability? A study protocol.BMC psychiatry · 2023Article
- Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health.Journal of medical Internet research · 2023Article
- Investigating the Physical and Mental Health Nexus: a Network Analysis of Depression, Cardiometabolic Health, Bone Mass, and Perceived Health Status Among Filipino Domestic Workers.International journal of behavioral medicine · 2023Article
- Article
- Examining the Autonomic Nervous System in the Relationship among Heart Rate Variability, Stress Coping, and Cognitive Ability in Individuals with Psychiatric Disorders.Journal of clinical medicine · 2022Article
- Stress-evoked muscle activity in women with and without chronic myofascial face pain.Journal of oral rehabilitation · 2021Article
- Using 24-h Heart Rate Variability to Investigate the Sleep Quality and Depression Symptoms of Medical Students.Frontiers in psychiatry · 2021Article
- Heart Rate Variability Changes in Patients With Major Depressive Disorder: Related to Confounding Factors, Not to Symptom Severity?Frontiers in neuroscience · 2021Article
- Evolution of Heart Rate Variability and Heart Rate Turbulence in Patients with Depressive Illness Treated with Selective Serotonin Reuptake Inhibitors.Medicina (Kaunas, Lithuania) · 2020Article
- Major depressive disorder and insomnia: Exploring a hypothesis of a common neurological basis using waking and sleep-derived heart rate variability.Journal of psychiatric research · 2020Article
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Authors and funding
9 authors.
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Abstract
Limitations of current depression treatments may arise from a lack of knowledge about unique psychophysiological processes that contribute to depression across the full range of presentations. This study examined how individual variations in heart rate (HR) and heart rate variability (HRV) are related to depressive symptoms across normative and clinical populations in 152 young adults (aged 18-35 years). Moderating effects of sex and antidepressant medication status were considered. Electrocardiogram data were collected during "vanilla" baseline and in response to positive and negative emotional cues. Linear regressions and repeated-measures mixed models were used to assess the relationships between Beck Depression Inventory-II (BDI-II) scores, sex, antidepressant use, and cardiovascular outcomes. Baseline models yielded significant main effects of BDI-II and sex on HR and significant interactions between antidepressant medication status and BDI-II on HRV outcomes. The main effects of BDI-II and sex on HR were no longer significant after controlling for cardiorespiratory fitness. Participants who denied current antidepressant use (n = 137) exhibited a negative association and participants who endorsed current antidepressant (n = 15) use exhibited a positive association between BDI-II scores and HRV. Emotional reactivity models were largely non-significant with the exception of a significant main effect of antidepressant medication status on high-frequency HRV reactivity. Results indicated antidepressant medication use may moderate the relationship between depression severity and cardiovascular functioning, but this requires replication given the modest proportion of medicated individuals in this study. Overall, findings suggest cardiovascular processes and cardiorespiratory fitness are linked to depression symptomatology and may be important to consider in depression treatment.
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