ArticleInsect molecular biology2020
Wolbachia transinfections in Culex quinquefasciatus generate cytoplasmic incompatibility.
Article in Insect molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of different X-ray irradiation dosages on Wolbachia trans-infected and uninfected Aedes aegypti mosquitoes.PLoS neglected tropical diseases · 2026Article
- Thermal sensitivity in a symbiont: effect of elevated cyclic temperature exposure on Wolbachia density in Culex quinquefasciatus (Diptera: Culicidae) embryos.Journal of insect science (Online) · 2026Article
- Article
- Extracellular microbes are required for mosquito development even in the presence of Wolbachia.PLoS neglected tropical diseases · 2025Article
- ExploitingPathogens (Basel, Switzerland) · 2025Review
- Multi-omics profiling reveals associations between gut microbiota and olfactory gene expression in mosquitoes.Frontiers in cellular and infection microbiology · 2025Article
- Potential effect ofFrontiers in microbiology · 2025Article
- Larvicidal activity ofCurrent research in parasitology & vector-borne diseases · 2025Article
- Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4).PLoS pathogens · 2024Article
- Review
- Article
- Holobiont perspectives on tripartite interactions among microbiota, mosquitoes, and pathogens.The ISME journal · 2023Review
- Article
- Characterizing the Wolbachia infection in field-collected Culicidae mosquitoes from Hainan Province, China.Parasites & vectors · 2023Article
- Characterization of the Bacterial Microbiome in Natural Populations of Barley Stem Gall Midge,Microorganisms · 2023Article
- NativeFrontiers in microbiology · 2023Article
- Wolbachia infection dynamics in a natural population of the pear psyllid Cacopsylla pyri (Hemiptera: Psylloidea) across its seasonal generations.Scientific reports · 2022Article
- Interspecies microbiome transplantation recapitulates microbial acquisition in mosquitoes.Microbiome · 2022Article
- Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the MosquitoThe CRISPR journal · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Culex quinquefasciatus is an important mosquito vector of a number of viral and protozoan pathogens of humans and animals, and naturally carries the endosymbiont Wolbachia pipientis, strain wPip. Wolbachia are used in two distinct vector control strategies: firstly, population suppression caused by mating incompatibilities between mass-released transinfected males and wild females; and secondly, the spread of pathogen transmission-blocking strains through populations. Using embryonic microinjection, two novel Wolbachia transinfections were generated in C. quinquefasciatus using strains native to the mosquito Aedes albopictus: a wAlbB single infection, and a wPip plus wAlbA superinfection. The wAlbB infection showed full bidirectional cytoplasmic incompatibility (CI) with wild-type C. quinquefasciatus in reciprocal crosses. The wPipwAlbA superinfection showed complete unidirectional CI, and therefore population invasion potential. Whereas the wAlbB strain showed comparatively low overall densities, similar to the native wPip, the wPipwAlbA superinfection reached over 400-fold higher densities in the salivary glands compared to the native wPip, suggesting it may be a candidate for pathogen transmission blocking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.