ArticlePloS one2019
Depression amongst patients commencing maintenance dialysis is associated with increased risk of death and severe infections: A nationwide cohort study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- A feasibility study of behavioural activation for haemodialysis: The BEACH study protocol.PloS one · 2026Article
- Temporal trends and disparities in mortality among US adults with chronic kidney disease and comorbid depression: a population-based analysis, 1999-2023.Frontiers in public health · 2026Article
- All-cause and cause-specific mortality in people with depression: a large-scale systematic review and meta-analysis of relative risk and aggravating or attenuating factors, including antidepressant treatment.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- The utility of brief instruments for depression screening in dialysis patients.Clinical kidney journal · 2025Article
- Psychological wellbeing and treatment adherence among cardio-renal syndrome patients in Yemen: a cross section study.Frontiers in medicine · 2024Article
- Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.Frontiers in nutrition · 2024Article
- Hierarchical multiple regression investigating factors associated with depressive symptoms in the middle-aged and elderly undergoing haemodialysis.BMC public health · 2023Article
- Decreased Intracellular to Total Body Water Ratio and Depressive Symptoms in Patients with Maintenance Hemodialysis.Psychology research and behavior management · 2023Article
- Article
- Health-related quality of life associated with risk of death in Brazilian dialysis patients: an eight-year cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Observational
- Study on the Application and Efficacy of Responsibility Nursing in Dialysis Care.Journal of healthcare engineering · 2021Article
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11 authors.
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Abstract
backgroundDepression is common in dialysis patients, but the clinical impact of this condition is poorly defined.
methodsOut of 57,703 patients starting dialysis during 2000-2007 recorded in the National Health Insurance Research Database of Taiwan, we identified 2,475 patients with a clinical diagnosis of depression, and compared them with 1:5 age- and sex-matched patients without a depression diagnosis (n = 12,375). Patients were followed up for hospitalisation due to severe infections, major adverse cardiovascular events (MACE) and death. Multivariable Cox regression and competing risk analyses (accounting for death when appropriate) were used to estimate risk associations.
resultsPatients with depression had a higher frequency of comorbidities. During a mean follow-up of 3.2 years, 1,140 severe infections, 806 MACE, and 1,121 deaths were recorded. Compared to controls, patients with depression were at increased risk of death (adjusted hazard ratio 1.24; 95%CI 1.16-1.33). Patients with depression were also at higher risk of severe (1.14; 1.06-1.22) and fatal infections (death within 30 days, 1.22; 1.09-1.35), attributed mainly to sepsis (1.19; 1.08-1.31), septic shock (1.36; 1.13-1.62) and pneumonia (1.19; 1.07-1.33). Conversely, no association was observed between depression and the MACE risk (1.04; 0.94-1.15).
conclusionDialysis patients with depression are associated with increased risk of infections and death.
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