ArticlePloS one2019
Comparative genome analysis reveals niche-specific genome expansion in Acinetobacter baumannii strains.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data.PLoS computational biology · 2019Pooled it
- The (un)successful global spread ofMicrobial genomics · 2026Article
- Siderophore-Pt(IV) Conjugates as Tools to Probe Cytoplasmic Cargo Delivery to Gram-Negative Bacteria.Journal of the American Chemical Society · 2026Article
- Isolation and whole-genome characterization of multidrug-resistant Acinetobacter baumannii from Indian retail meat: unveiling high-risk clones and zoonotic transmission threats via comparative genomics.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Genomic landscape of nosocomial Acinetobacter baumannii: A comprehensive analysis of the resistome, virulome, and mobilome.Scientific reports · 2025Article
- Positron Emission Tomography Imaging ofACS infectious diseases · 2025Article
- A leucine responsive small RNA AbcR200 regulates expression of the lactate utilization (lut) operon in Acinetobacter baumannii DS002.The Journal of biological chemistry · 2025Article
- Genomic insights into biofilm-associated virulence in extensively drug-resistantCurrent research in microbial sciences · 2025Article
- Outer membrane vesicles ofMicrobiology spectrum · 2024Article
- Phenotypic and Molecular Characterization of Hypervirulent and Multidrug-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024Article
- A bioinformatic approach to identify confirmed and probable CRISPR-Cas systems in theFrontiers in microbiology · 2024Article
- Article
- Acinetobacter Metabolism in Infection and Antimicrobial Resistance.Infection and immunity · 2023Review
- Whole-Genome Sequencing-Based Resistome Analysis of Nosocomial Multidrug-Resistant Non-Fermenting Gram-Negative Pathogens from the Balkans.Microorganisms · 2023Review
- Wastewater treatment plants, an "escape gate" for ESCAPE pathogens.Frontiers in microbiology · 2023Review
- Extensively drug-resistantPeerJ · 2023Article
- Tn6553, a Tn7-family transposon encoding putative iron uptake functions found in Acinetobacter.Archives of microbiology · 2022Article
- Comparative Genomics Reveals Genetic Diversity and Metabolic Potentials of the GenusMicrobiology spectrum · 2022Article
- Outer Membrane Vesicles ofMicrobiology spectrum · 2022Article
- Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-ResistantInternational journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nosocomial pathogen Acinetobacter baumannii acquired clinical significance due to the rapid development of its multi-drug resistant (MDR) phenotype. A. baumannii strains have the ability to colonize several ecological niches including soil, water, and animals, including humans. They also survive under extremely harsh environmental conditions thriving on rare and recalcitrant carbon compounds. However, the molecular basis behind such extreme adaptability of A. baumannii is unknown. We have therefore determined the complete genome sequence of A. baumannii DS002, which was isolated from agricultural soils, and compared it with 78 complete genome sequences of A. baumannii strains having complete information on the source of their isolation. Interestingly, the genome of A. baumannii DS002 showed high similarity to the genome of A. baumannii SDF isolated from the body louse. The environmental and clinical strains, which do not share a monophyletic origin, showed the existence of a strain-specific unique gene pool that supports niche-specific survival. The strains isolated from infected samples contained a genetic repertoire with a unique gene pool coding for iron acquisition machinery, particularly those required for the biosynthesis of acinetobactin. Interestingly, these strains also contained genes required for biofilm formation. However, such gene sets were either partially or completely missing in the environmental isolates, which instead harbored genes required for alternate carbon catabolism and a TonB-dependent transport system involved in the acquisition of iron via siderophores or xenosiderophores.
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