Evidence map›Paper›PMID 31194704›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study.

Wafaa M El-Sadr, Geetha Beauchamp, H Irene Hall, Lucia V Torian, Barry S Zingman, Garret Lum, Richard A Elion, Kate Buchacz, David Burns, Allison Zerbe and 3 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wafaa M El-SadrICAP at Columbia University, New York, NY.
Geetha BeauchampVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
H Irene HallCenters for Disease Control and Prevention, Atlanta, GA.
Lucia V TorianNew York City Department of Health and Mental Hygiene, Long Island City, NY.
Barry S ZingmanMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Garret LumDistrict of Columbia Department of Health, HIV/AIDS, Hepatitis, STD and TB Administration, Washington, DC.
Richard A ElionGeorge Washington University, School of Medicine, Washington, DC.
Kate BuchaczCenters for Disease Control and Prevention, Atlanta, GA.
David BurnsDivision of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD.
Allison ZerbeICAP at Columbia University, New York, NY.
Theresa GambleHPTN Leadership and Operations Center, FHI 360, Durham, NC.
Deborah J DonnellVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
HPTN 065 Study

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619
6 · The paper itself

Abstract

backgroundResults from the HPTN 065 study showed that financial incentives (FI) were associated with significantly higher viral load suppression and higher levels of engagement in care among patients at HIV care sites randomized to FI versus sites randomized to standard of care (SOC). We assessed HIV viral suppression and continuity in care after intervention withdrawal to determine the durability of FI on these outcomes.

settingA total of 37 HIV test and 39 HIV care sites in the Bronx, New York, and Washington, DC, participated in the study.

methodsLaboratory data reported to the US National HIV Surveillance System were used to determine site-level viral suppression and continuity in care outcomes. Postintervention effects were assessed for the 3 quarters after discontinuation of FI. Generalized estimation equations were used to compare FI and SOC site-level outcomes after intervention withdrawal.

resultsAfter FI withdrawal, a trend remained for an increase in viral suppression by 2.7% (-0.3%, 5.6%, P = 0.076) at FI versus SOC sites, decreasing from the 3.8% increase noted during implementation of the intervention. The significant increase in continuity in care during the FI intervention was sustained after intervention with 7.5% (P = 0.007) higher continuity in care at FI versus SOC sites.

conclusionsAfter the withdrawal of FI, findings at the 9-months postintervention withdrawal from this large study showed evidence of durable effects of FI on continuity in care, with trend for continued higher viral suppression. These findings are promising for adoption of such interventions to enhance key HIV-related care outcomes.

Indexed as

Continuity of Patient CareViral LoadAdolescentAdultAge FactorsHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedMotivationSexual PartnersUnsafe SexYoung Adult

Identifiers

PMID31194704
PMCPMC6587372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.