ReviewActa pharmaceutica Sinica. B2019
Recent advances of microneedles for biomedical applications: drug delivery and beyond.
Review in Acta pharmaceutica Sinica. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
120 citing papers in PubMed.
- Economic analysis of microneedle technology: cost-effectiveness, manufacturing scalability, and commercialization challenges.Drug delivery and translational research · 2026Review
- Microneedle patch technologies in virology: bridging immunization, antiviral therapy, and point-of-care diagnostics.Clinical and experimental vaccine research · 2026Review
- Biomimetic Material Selection for Therapeutic Microneedles: An Analytic Hierarchy Process-Based Multi-Criteria Evaluation.Polymers · 2026Article
- Application of ultrasound and ultrasound-responsive materials in wounds: A systematic review.International journal of pharmaceutics: X · 2026Review
- Core-shell microneedles Co-loaded with simvastatin and doxycycline for combined anti-infection and osteogenesis in diabetic periodontitis.Materials today. Bio · 2026Article
- Bionic microneedles: Design inspired by bionics and its applications in medicine.International journal of pharmaceutics: X · 2026Review
- Review
- Cytokine-Engineered Chimeric Antigen Receptor-T Cell Therapy: How to Balance the Efficacy and Toxicity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges.Advanced healthcare materials · 2026Review
- Vertical graphene-coated core-shell microneedle as miniatured sensor for in vivo glucose monitoring.Microsystems & nanoengineering · 2026Article
- Smart patches for healthcare industry: a review of emerging technologies, challenges, and developmental opportunities.Biomedical engineering online · 2026Review
- Microneedle Technologies for Drug Delivery: Innovations, Applications, and Commercial Challenges.Micromachines · 2026Review
- Microneedle-Assisted Cell Delivery and Therapy.Research (Washington, D.C.) · 2026Review
- Advances in microneedle design for the delivery of drugs, proteins, and cells in the treatment of hypertrophic scars.Burns & trauma · 2026Review
- Upconverting Nanoparticle-Loaded Microneedles for Near-Infrared Responsive Delivery of Gonadotropins to Increase Success of In Vitro Fertilization.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Recent progress of NIR light-controlled microneedles and therapeutic applications: A review study.Journal of materials science. Materials in medicine · 2025Review
- Advances in 3D Printed Microneedles as a Prototype for Skin Targeted Therapeutics in Personalized Dermal Pharmaceuticals.AAPS PharmSciTech · 2025Review
- Hydrogel-forming microneedles for the treatment of skin diseases.Materials today. Bio · 2025Review
- 3D necroprinting: Leveraging biotic material as the nozzle for 3D printing.Science advances · 2025Article
- Recent advances in electric-stimulus assisted microneedle patches for skin disease treatment.Journal of nanobiotechnology · 2025Review
60 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The microneedle (MN), a highly efficient and versatile device, has attracted extensive scientific and industrial interests in the past decades due to prominent properties including painless penetration, low cost, excellent therapeutic efficacy, and relative safety. The robust microneedle enabling transdermal delivery has a paramount potential to create advanced functional devices with superior nature for biomedical applications. In this review, a great effort has been made to summarize the advance of microneedles including their materials and latest fabrication method, such as three-dimensional printing (3DP). Importantly, a variety of representative biomedical applications of microneedles such as disease treatment, immunobiological administration, disease diagnosis and cosmetic field, are highlighted in detail. At last, conclusions and future perspectives for development of advanced microneedles in biomedical fields have been discussed systematically. Taken together, as an emerging tool, microneedles have showed profound promise for biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.