Evidence map›Paper›PMID 31193798›Full record

ArticleAddictive behaviors reports2019

A structural MRI study of differential neuromorphometric characteristics of binge and heavy drinking.

Arkadiy L Maksimovskiy, Catherine B Fortier, William P Milberg, Regina E McGlinchey

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Addictive behaviors reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The ventral pallidum and relapse in alcohol seeking.British journal of pharmacology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Arkadiy L MaksimovskiyTranslational Research Center for TBI and Stress-related Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States of America.
Catherine B FortierTranslational Research Center for TBI and Stress-related Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States of America.
William P MilbergTranslational Research Center for TBI and Stress-related Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States of America.
Regina E McGlincheyTranslational Research Center for TBI and Stress-related Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States of America.
Geriatric Research Education and Clinical Center · USHarvard University · USVA Boston Healthcare System · US

Funding

Associative learning and brain structure in individuals at risk for dementiaK23AG034258 · NIA · HARVARD MEDICAL SCHOOL · PI FORTIER, CATHERINE BRAWN · 2010 to 2014
$783k
Structural & Functional Brain Alterations Related to Adolescent Binge DrinkingI01CX001327 · VA · VA BOSTON HEALTH CARE SYSTEM · PI MCGLINCHEY, REGINA · 2016 to 2020
–
CSRD VA I01 CX001327NIA NIH HHS K23 AG034258RRD VA I50 RX003001
6 · The paper itself

Abstract

backgroundAlcohol misuse often manifests in two different patterns of drinking; Binge Drinking (BD; ≥4 (women) or ≥ 5 (men) drinks/day, ≤12 days/month) or Heavy Drinking (HD; ≥3 (women) or ≥4 (men) drinks/day, ≥16 days/month). Although direct comparisons have not been made, structural MRI studies indicate that the two types of drinking behaviors might be associated with different neuromorphometric characteristics.

methodsThis study used a cross-sectional design to compare brain structure (using MRI derived subcortical volume and cortical thickness measures) between participants with histories of BD (

resultsBD was associated with decreased volumes of the bilateral global pallidus and decreased cortical thickness within the left superior-parietal cluster (

conclusionsThese data indicate that histories of BD and HD patterns are associated with distinct neuromorphometric characteristics. BD was associated with changes within the executive control networks and the globus pallidus. HD was associated with widespread changes, that are primarily localized within the visual network.

Indexed as

AlcoholBinge drinkingBrain volumeCortical thicknessHeavy drinking

Identifiers

PMID31193798
PMCPMC6542838
OpenAlexW2917187791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.