ReviewHeliyon2019
Bisphenol A in dental materials - existence, leakage and biological effects.
Review in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Toxicity of resin-matrix composites in a dental clinical setting.Odontology · 2025Pooled it
- Germ cell risk assessment of combined exposure to monosodium glutamate and bisphenol A in male SD rat: deciphering the molecular mechanisms.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Cumulative Bisphenol A Release and Elution Kinetics from Pediatric Restorative and Orthodontic Resin-Based Materials: An In Vitro LC-MS/MS Investigation.Children (Basel, Switzerland) · 2026Article
- Bisphenol-A Release from Modern Resin-Based Dental Composites: A Time-Dependent In Vitro Assessment.Polymers · 2026Article
- Bisphenol A in contemporary dentistry: from material chemistry and exposure pathways to potential clinical relevance-a comprehensive narrative review.Frontiers in dental medicine · 2026Review
- Protective role of Karanjin against bisphenol A-Induced cognitive deficits and oxidative damage in a zebrafish model.Scientific reports · 2025Article
- Mitigating the environmental effects of healthcare: the role of the endocrinologist.Nature reviews. Endocrinology · 2025Review
- Do Clear Aligners Release Toxic Chemicals?-A Systematic Review.Journal of functional biomaterials · 2025Review
- Evaluation of the Genotoxicity and Cytotoxicity of Bioceramic Endodontic Sealers in HepG2 and V79 Cell Lines: An In Vitro Study Using the Comet and Micronucleus Assays.Journal of functional biomaterials · 2025Article
- Clinical performance of different composite materials in class II cavities bonded with universal adhesives.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Article
- Surface alterations and compound release from aligner attachments in vitro.European journal of orthodontics · 2024Article
- Salivary levels of eluents during Invisalign™ treatment with attachments: an in vivo investigation.Progress in orthodontics · 2024Article
- Effects of Behavioral, Clinical, and Policy Interventions in Reducing Human Exposure to Bisphenols and Phthalates: A Scoping Review.Environmental health perspectives · 2024Article
- Comparative In Vitro Biocompatibility Study of the Two Orthodontic Bonding Materials of Different Types.Polymers · 2022Article
- Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach.Polymers · 2022Article
- Fast self-curing α-tricalcium phosphate/β-dicalcium silicate composites beneficial for root canal sealing treatment.Heliyon · 2022Article
- Hair Sample Analysis of Residents from Olsztyn, Northeastern Poland, to Evaluate Levels of Bisphenol S and Bisphenol A: A Pilot Study.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Bisphenol A Release from Dental Composites and Resin-Modified Glass Ionomers under Two Polymerization Conditions.Polymers · 2021Article
- Release of Bisphenol A from Milled and 3D-Printed Dental Polycarbonate Materials.Materials (Basel, Switzerland) · 2021Article
- Protective effects of selenium on Bisphenol A-induced oxidative stress in mouse testicular mitochondria and sperm motility.JBRA assisted reproduction · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveRecently, questions have been raised concerning the potential endocrine disrupting effects of bisphenol A (BPA). This substance is a constituent in many different products which we frequently come into contact with, such as food containers and receipts. Resin-based dental filling materials are another source of exposure, although according to previous studies the amount and potential risks are not clear. Thus, the aims of the present study were (1) to identify if direct dental filling materials are liable to leak BPA and (2) to investigate if this leakage could lead to any adverse effects on health. MATERIALS AND
methodsA literature search was made with PubMed as the primary source, subsequently complemented with reference tracking.
resultsA total of 26 articles were included, 24 of which were used for the first aim (leakage) and 2 for the second aim (health risks). The majority of studies, including all in vivo studies, showed leakage of BPA from dental materials in various amounts and during different time intervals. The findings showed a contradiction in results regarding the connection between dental materials and adverse health effects.
conclusionsThere is leakage of BPA from some dental materials, but critical levels are not evident. Bis-DMA contents might convert to BPA in the oral cavity. There is a contradiction between in vitro and in vivo studies concerning BPA leakage and finally, there is a lack of studies investigating the association between BPA exposure and its adverse effects on human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.