ArticleEClinicalMedicine
What Works in Youth Suicide Prevention? A Systematic Review and Meta-Analysis.
Article in EClinicalMedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 20 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 20 syntheses or guidelines pooled it, 241 citations in OpenAlex.
- Review: Adolescents' perspectives on and experiences with post-primary school-based suicide prevention as end-users, co-creators and peer helpers - a systematic review meta-ethnography.Child and adolescent mental health · 2026Pooled it
- Gender in suicide prevention in adolescents and young adults: a systematic review.BMC public health · 2026Pooled it
- Effectiveness of suicide means restriction: an overview of systematic reviews.BMJ mental health · 2025Pooled it
- Community-based mental health interventions for reducing youth suicidal thoughts and behaviours: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Effectiveness of Suicide Prevention Programmes Among Adolescents and Sociocultural Adaptation of Programmes: A Systematic Review.International journal of mental health nursing · 2025Pooled it
- Prevention of self-harm and suicide in young people up to the age of 25 in education settings.The Cochrane database of systematic reviews · 2024Pooled it
- Quantifying the Representation of Black Adolescents in Suicide Intervention Research.Research on child and adolescent psychopathology · 2024Pooled it
- Psychosocial interventions for suicidal and self-injurious-related behaviors among adolescents: a systematic review and meta-analysis of Chinese practices.Frontiers in public health · 2023Pooled it
- Systematic review of suicide prevention studies with data on youth and young adults living in low-income and middle-income countries.BMJ open · 2022Pooled it
- Research Review: The effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression.Journal of child psychology and psychiatry, and allied disciplines · 2022Pooled it
- A mixed-methods systematic review of suicide prevention interventions involving multisectoral collaborations.Health research policy and systems · 2022Pooled it
- Ineligibility for and Refusal to Participate in Randomized Controlled Trials That Have Studied Impact on Suicide-Related Outcomes in the United States: A Meta-Analysis.The Journal of clinical psychiatry · 2022Pooled it
- Systematic review and narrative synthesis of suicide prevention in high-schools and universities: a research agenda for evidence-based practice.BMC public health · 2021Pooled it
- Comparative Efficacy and Acceptability of Psychotherapies for Self-harm and Suicidal Behavior Among Children and Adolescents: A Systematic Review and Network Meta-analysis.JAMA network open · 2021Pooled it
- Interventions for self-harm in children and adolescents.The Cochrane database of systematic reviews · 2021Pooled it
- The Role of New Technologies to Prevent Suicide in Adolescence: A Systematic Review of the Literature.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Internet-Based Cognitive Behavioral Therapy to Reduce Suicidal Ideation: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Association of suicidal behavior with exposure to suicide and suicide attempt: A systematic review and multilevel meta-analysis.PLoS medicine · 2020Pooled it
- Effectiveness of universal programmes for the prevention of suicidal ideation, behaviour and mental ill health in medical students: a systematic review and meta-analysis.Evidence-based mental health · 2019Pooled it
- Are we Using the Right Evidence to Inform Suicide Prevention in Low- and Middle-Income Countries? An Umbrella Review.Archives of suicide research : official journal of the International Academy for Suicide ResearchPooled it
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundYoung people require specific attention when it comes to suicide prevention, however efforts need to be based on robust evidence.
methodsWe conducted a systematic review and meta-analysis of all studies examining the impact of interventions that were specifically designed to reduce suicide-related behavior in young people.
findingsNinety-nine studies were identified, of which 52 were conducted in clinical settings, 31 in educational or workplace settings, and 15 in community settings. Around half were randomized controlled trials. Large scale interventions delivered in both clinical and educational settings appear to reduce self-harm and suicidal ideation post-intervention, and to a lesser extent at follow-up. In community settings, multi-faceted, place-based approaches seem to have an impact. Study quality was limited.
interpretationOverall whilst the number and range of studies is encouraging, gaps exist. Few studies were conducted in low-middle income countries or with demographic populations known to be at increased risk. Similarly, there was a lack of studies conducted in primary care, universities and workplaces. However, we identified that specific youth suicide-prevention interventions can reduce self-harm and suicidal ideation; these types of intervention need testing in high-quality studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.