Evidence map›Paper›PMID 31193417›Full record

ArticleSSM - population health2019

Establishing a causal link between social relationships and health using the Bradford Hill Guidelines.

Jeremy Howick, Paul Kelly, Mike Kelly

Erratum issuedAbstract read
In one paragraph

Article in SSM - population health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Are social isolation, lack of social support or loneliness risk factors for cardiovascular disease in Australia and New Zealand? A systematic review and meta-analysis.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2022
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  14. Social connection as a critical factor for mental and physical health: evidence, trends, challenges, and future implications.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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  18. Observational
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  20. Navigating Black Aging: The Biological Consequences of Stress and Depression.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jeremy HowickUniversity of Oxford, Nuffield Department of Primary Care Health Science, Faculty of Philosophy, 32 Woodstock Road, Oxford, OX2 6GG, United Kingdom.
Paul KellyUniversity of Edinburgh, Sport, Physical Education and Health Sciences (SPEHS), Moray House School of Education, United Kingdom.
Mike KellyUniversity of Cambridge, Department of Public Health and Primary Care, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An abundance of evidence suggests that the size and quality of our social relationships improves humans' physical and mental health while increasing lifespan. However most of this evidence comes from observational rather than experimental (randomised trial) evidence, leaving open the possibility that the connection between social relationships and health could be associational rather than causal. However there are examples, including the link between smoking and lung cancer, where a cause was established without experimental evidence. This was sometimes achieved by looking at the totality of evidence, using the 'Bradford Hill Guidelines', which considers factors including the strength of association, reversibility, and evidence of a plausible mechanism. In this paper we apply the Bradford Hill Guidelines to the link between social relationships and health. We conclude that having strong and supportive social relationships causes better health and longer life. Beyond establishing that social relationships are a causal factor for health, the method we used here can be applied to other areas where randomised trials are unethical or not feasible.

Indexed as

Bradford HillCausationEvidence-based medicineExperimentHealthRandomised trialSocial networksSocial relationshipsUrban planning

Identifiers

PMID31193417
PMCPMC6527915

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.