Evidence map›Paper›PMID 31193388›Full record

ArticleEuropean journal of radiology open2019

Thyroid-associated Orbitopathy: Quantitative Evaluation of the Orbital Fat Volume and Edema Using IDEAL-FSE.

Yoko Kaichi, Keizo Tanitame, Hiroaki Terada, Hideki Itakura, Haruya Ohno, Masayasu Yoneda, Yuji Takahashi, Yuji Akiyama, Kazuo Awai

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In one paragraph

Article in European journal of radiology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoko KaichiDiagnostic Radiology, Graduate School and Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Keizo TanitameDepartment of Diagnostic Radiology, Hiroshima Prefectural Hospital, Ujinakanda 1-5-54, Minami-ku, Hiroshima 734-8530, Japan.
Hiroaki TeradaDiagnostic Radiology, Graduate School and Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Hideki ItakuraItakura Eye Clinic, Ochiai 5-24-8, Asakita-ku, Hiroshima 739-1731, Japan.
Haruya OhnoDepartment of Molecular and Internal Medicine, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Masayasu YonedaDepartment of Molecular and Internal Medicine, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Yuji TakahashiDepartment of Clinical Radiology, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Yuji AkiyamaDiagnostic Radiology, Graduate School and Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Kazuo AwaiDiagnostic Radiology, Graduate School and Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTo compare orbital quantitative data obtained by fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL) in patients with thyroid-associated orbitopathy (TAO) and healthy controls and to investigate the characteristics of these data in TAO patients. MATERIALS AND

methodsTwenty-two TAO patients (4 males and 18 females; median age 51.0 years) and 22 healthy subjects (5 males and 17 females; median age 50.5 years) underwent orbital T2-weighted FSE-IDEAL. The water fraction in orbital fat was defined as the signal intensity (SI)

resultsIn TAO patients, the water fraction (right and left, p = 0.04), fat volume (right and left, p = 0.03) and degree of proptosis (right and left, p < 0.01) were higher than in the controls. In TAO patients, only the water fraction and the fat volume of left orbit showed negative correlation (p = 0.01).

conclusionThe water fraction of orbital fat, the orbital fat volume and the degree of proptosis obtained with FSE-IDEAL were higher in TAO patients than in the controls. The water fraction was a new parameter for differentiating between TAO patients and healthy subjects.

Indexed as

CAS, clinical activity scorefast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL)FSE-IDEAL, fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimationIQR, interquartile rangeorbital fat volumeproptosisquantitative evaluationSD, standard deviationSI, signal intensityTAO, thyroid-associated orbitopathythyroid-associated orbitopathy (TAO)water fraction

Identifiers

PMID31193388
PMCPMC6526225

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.