Evidence map›Paper›PMID 31193218›Full record

ArticleHeliyon2019

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer

Chandrabose Karthikeyan, Haneen Amawi, Charles R Ashby, Vishwa M Khare, Veronica Jones, N S Hari Narayana Moorthy, Piyush Trivedi, Amit K Tiwari

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Chandrabose KarthikeyanDepartment of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, 484887, India.
Haneen AmawiDepartment of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, OH, USA.
Charles R AshbyDepartment of Pharmaceutical Sciences, St. John's University, Queens, USA.
Vishwa M KhareCell and Developmental Biology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Veronica JonesDepartment of Biomedical Sciences, Tuskegee University, Tuskegee, AL, USA.
N S Hari Narayana MoorthyDepartment of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, 484887, India.
Piyush TrivediSchool of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, 462036, India.
Amit K TiwariDepartment of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, OH, USA.
Indira Gandhi National Tribal University · INTuskegee University · USBharati Vidyapeeth Deemed University · INSt. John's University · USUniversity of Pennsylvania · USYarmouk University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the 'molecular hybridization approach' and evaluated for anticancer efficacy. Eleven 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones (

Indexed as

Natural product chemistryPharmaceutical chemistryPharmaceutical science

Identifiers

PMID31193218
PMCPMC6522656
OpenAlexW2945742930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.