Evidence map›Paper›PMID 31193067›Full record

ArticleJournal of clinical & translational endocrinology2019

The differences in the relationship between obstructive sleep apnea severity and trabecular bone score in men and women with type 2 diabetes.

Hataikarn Nimitphong, Nantaporn Siwasaranond, Chanika Sritara, Sunee Saetung, La-Or Chailurkit, Naricha Chirakalwasan, Boonsong Ongphiphadhanakul, Sirimon Reutrakul

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In one paragraph

Article in Journal of clinical & translational endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hataikarn NimitphongDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Nantaporn SiwasaranondDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chanika SritaraDepartment of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sunee SaetungDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
La-Or ChailurkitDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Naricha ChirakalwasanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Boonsong OngphiphadhanakulDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sirimon ReutrakulDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsType 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA) may adversely affect bone. Gender is a well-established factor influencing bone health. We investigated the impact of OSA on bone mineral density (BMD) and trabecular bone score (TBS) in T2DM.

methodsEighty-one T2DM patients [33 men and 48 women] participated. OSA was diagnosed using an overnight monitor, with its severity assessed by an apnea hypopnia index (pAHI). The measurements of hypoxia, including the percentage of total sleep time in which oxygen saturation remains below 90% (pT90), the oxygen desaturation index (pODI) and minimum O

resultsSixty-five patients (80.2%) had OSA. pAHI, pT90, pODI and min O

conclusionsIn T2DM patients, there is a complex interrelationship among OSA severity, gender and TBS. More severe OSA predicted lower TBS in men, but predicted higher TBS in postmenopausal women.

Indexed as

aBMD, areal bone mineral densityApnea–hypopnea index (AHI)BMD, bone mineral densityBMD/TBSBMI, body mass indexCV, coefficient of variationDXA, dual-energy X-ray absorptiometryFN, femoral neckGenderHbA1c, hemoglobin A1cHRpQCT, high resolution peripheral quantitative computed tomographyIQR, interquartile rangeISCD, International Society for Clinical DensitometryL1-4, lumbar spine 1-4Menopausal statusmin O2, minimum O2Obstructive sleep apneaOSA, obstructive sleep apneapAHI, PAT-derived apnea hypopnia indexPMW, postmenopausal womenpODI, PAT-derived oxygen desaturation indexp, peripheral arterial tone (PAT)pT90, PAT-derived T90RMS, root mean squareSD, standard deviationT2DM, type 2 diabetes mellitusTBS, trabecular bone scoreType 2 diabetes

Identifiers

PMID31193067
PMCPMC6514725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.