SynthesisMedicine2019
Is it safe to perform gastrectomy in gastric cancer patients aged 80 or older?: A meta-analysis and systematic review.
Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Prognostic impact of postoperative complications among elderly patients with gastric cancer.PloS one · 2026Article
- Survival benefits of postoperative adjuvant chemotherapy in adults aged ≥ 80 years with locally advanced gastric cancer: insights from a population-based study.Discover oncology · 2025Article
- Construction and validation of a novel nomogram based on the log odds of positive lymph nodes to predict cancer-specific survival in elderly patients with gastric adenocarcinoma after radical surgery.BMC gastroenterology · 2025Article
- Risk factors for serious postoperative complications following gastrectomy in super-elderly patients ≥85-years-old with gastric cancer: A National Clinical Database study in Japan.Annals of gastroenterological surgery · 2025Article
- Article
- Efficacy of a new immunonutrition formula with extra virgin olive oil in the reduction of complications in surgeries of upper digestive tract tumors.Frontiers in nutrition · 2024Article
- Outcomes of Gastrectomy for Gastric Cancer in Patients Aged >80 Years: A Systematic Literature Review and Meta-Analysis.Journal of gastric cancer · 2023Review
- Impact of Age on the Treatment and Survival in Esophagogastric Cancer.Annals of surgical oncology · 2023Article
- ASO Author Reflections: Increasing Age is Associated with Increased Risk of Long-Term Mortality After Surgery and Non-operation in Esophagogastric Cancer Patients.Annals of surgical oncology · 2023Article
- Changes in failure to rescue after gastrectomy at a large-volume center with a 16-year experience in Korea.Scientific reports · 2023Article
- Survival analyses of elderly gastric cancer patients with or without surgery.Surgery today · 2022Article
- Laparoscopic distal gastrectomy in old-old patients: the first Western experience.Updates in surgery · 2021Article
- GASTRECTOMY IN OCTOGENARIANS WITH GASTRIC CANCER: IS IT FEASIBLE?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021Article
- Feasibility and safety of an enhanced recovery protocol (ERP) for upper GI surgery in elderly patients (≥ 75 years) in a high-volume surgical center.Updates in surgery · 2020Article
- Short- and Long-term Outcome After Gastric Cancer Resection in Patients Aged 80 Years and Older.Cancer diagnosis & prognosisArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have focused on octogenarian patients with gastric cancer (GC) who have undergone gastrectomy. This meta-analysis of published studies was performed to assess the safety of treating octogenarian GC patients with surgery.
methodsDatabases, including PubMed, Embase, Web of Science, and Cochrane Library were searched until January 2019. The incidence of preoperative comorbidities, postoperative complications, and mortality was assessed using odds ratios (ORs) with corresponding 95% confidence intervals (CIs). Further, the hazard ratios (HRs) with 95% CIs were applied for survival outcomes.
resultsA total of 18,179 patients with GC in 21 studies were included. Our results demonstrated that octogenarian patients were associated with a higher burden of comorbidities (OR = 2.79; 95% CI: 2.37, 3.28; P = .00), high incidences of overall postoperative complications (OR = 1.48; 95% CI: 1.22, 1.81; P = .00), medical postoperative complications (OR = 2.58; 95% CI: 1.91, 3.49; P = .00), in-hospital mortality (OR = 3.24; 95% CI: 2.43, 4.31; P = .00) and poor overall survival (HR = 1.96; 95% CI: 1.65, 2.27; P = .00).
conclusionsConsidering the high burden of comorbidities, high incidences of postoperative complications and mortality, surgery for extremely elderly patients with GC requires deliberation. Individualized treatment is recommended for such patients.
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