Evidence map›Paper›PMID 31192966›Full record

ArticleMedicine2019

A nomogram for predicting survival in patients with nodular melanoma: A population-based study.

Jin Yang, Zhenyu Pan, Fanfan Zhao, Xiaojie Feng, Qingqing Liu, Yuanjie Li, Jun Lyu

Abstract readValidation Study
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Cell Death Modalities in Therapy of Melanoma.International journal of molecular sciences · 2025
    Review
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  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin YangClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.
Zhenyu PanClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.
Fanfan ZhaoClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.
Xiaojie FengClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.
Qingqing LiuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.
Yuanjie LiDepartment of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi.
Jun LyuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of traditional American Joint Committee on Cancer (AJCC) staging alone has limitations in predicting patient survival with nodular melanoma (NM). We aimed to establish a comprehensive prognostic nomogram and compare its prognostic value with the AJCC staging system.A nomogram was constructed to predict the 3-year and 5-year survival rates of NM patients by Cox regression. Several common model-validation parameters were used to evaluate the performance of our survival model.The multivariate analyses demonstrated that the age at diagnosis; being divorced, separated, or widowed; AJCC stages II, III, and IV; a regional SEER stage and the lymph-node density (LND) were risk factors for survival. The concordance index, the area under the time-dependent receiver operating characteristic curve, and calibration plots indicated that the nomogram performed well, while the net reclassification improvement and the integrated discrimination improvement showed that the nomogram performed better than the AJCC staging system. Finally, the decision curve analyses curves of the nomogram yielded net benefits that were higher than when using AJCC staging system with either the training or the validation cohort.The prognostic value of the nomogram is better than that of the AJCC staging system alone. In addition, we found that LND is an important risk factor for the survival of NM patients. The nomogram developed in this study may be a valuable tool for clinical practice when advising patients about their survival risk over the next 3 to 5 years.

Indexed as

AgedCohort StudiesFemaleHumansMaleMelanomaMiddle AgedMultivariate AnalysisNeoplasm StagingNomogramsRisk AssessmentROC CurveSEER ProgramSkin NeoplasmsSurvival Analysis

Identifiers

PMID31192966
PMCPMC6587643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.