Evidence map›Paper›PMID 31192873›Full record

ArticleThe journal of ECT2020

Clinical Effectiveness of Maintenance Electroconvulsive Therapy in Patients with Schizophrenia: A Retrospective Cohort Study.

Moshe Isserles, Jesse Remington, Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger

Open access · greenAbstract read
In one paragraph

Article in The journal of ECT, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Faradization for insomnia: a sleep neurology history.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Moshe Isserles
Jesse RemingtonFrom the Temerty Centre for Therapeutic Brain Intervention, Campbell Family Research Institute, Centre for Addiction and Mental Health.
Tyler S Kaster
Zafiris J Daskalakis
Daniel M Blumberger
Centre for Addiction and Mental Health · CAUniversity of Toronto · CA

Funding

Confirmatory Safety and Efficacy Trial of Magnetic Seizure Therapy for DepressionR01MH112815 · NIMH · CENTRE FOR ADDICTION AND MENTAL HEALTH · PI BLUMBERGER, DANIEL M., DASKALAKIS, ZAFIRIS J. · 2017 to 2023
$7.4M
NIMH NIH HHS R01 MH112815
6 · The paper itself

Abstract

objectiveThis study aimed to assess the clinical effectiveness and cognitive effects of maintenance electroconvulsive therapy (mECT) in patients with schizophrenia or schizoaffective disorder and explore factors associated with both outcomes.

methodsIn this retrospective cohort study, we examined clinical records of 47 patients with a Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) diagnosis of schizophrenia or schizoaffective disorder treated with mECT at an academic mental health hospital between April 2010 and July 2016. Sixty-two mECT courses were reviewed. We assessed clinical effectiveness and cognitive effects as well as factors associated with response to treatment, including psychiatric diagnosis, concomitant pharmacological treatment, and previous treatment response.

resultsMaintenance electroconvulsive therapy was able to maintain clinical response in 48 (77%) treatment courses. Significant cognitive adverse effects were reported in 7 (11%) of the courses. Use of antipsychotic, antidepressant or benzodiazepine medications, psychiatric disorder, and sex were not associated with response.

conclusionThis study shows meaningful clinical effectiveness and good tolerability of mECT in patients with resistant schizophrenia over extended periods.

Indexed as

Electroconvulsive TherapyAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeuropsychological TestsOntarioPsychotic DisordersRetrospective StudiesSchizophreniaTreatment Outcome

Identifiers

PMID31192873
PMCPMC6904542
OpenAlexW2952801529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.