ArticleNeuropsychology2020
Intraindividual variability in verbal fluency performance is moderated by and predictive of mild cognitive impairments.
Article in Neuropsychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Meta-analysis of Controlled Oral Word Association Test (COWAT) FAS performance in amnestic mild cognitive impairment and cognitively unimpaired older adults.Applied neuropsychology. AdultPooled it
- Longitudinal decline in semanticJournal of the International Neuropsychological Society : JINS · 2023Article
- Gray matter volume and within-task verbal fluency performance among older adults.Brain and cognition · 2023Article
- Bear in mind: the role of personal background in semantic animal fluency - The SMART-MR study.Frontiers in psychology · 2023Article
- Association among race/color, gender, and intrinsic capacity: results from the ELSI-Brazil study.Revista de saude publica · 2023Article
- Associations between anxiety, centromedial amygdala volume, and complex verbal fluency in middle-aged to older adults.Journal of clinical and experimental neuropsychology · 2022Article
- Chinese expert consensus on assessment of cognitive impairment in the elderly.Aging medicine (Milton (N.S.W)) · 2022Article
- Assessing within-task verbal fluency performance: the utility of individual time intervals in predicting incident mild cognitive impairment.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2021Article
- Cognitive Dispersion Predicts Grip Strength Trajectories in Men but not Women in a Sample of the Oldest Old Without Dementia.Innovation in aging · 2021Article
- Intraindividual variability in neural activity in the prefrontal cortex during active walking in older adults.Psychology and aging · 2020Article
- Mild Cognitive Impairments Attenuate Prefrontal Cortex Activations during Walking in Older Adults.Brain sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe current study was designed to achieve 2 primary objectives: (a) determine the moderating effect of mild cognitive impairments (MCI) on intraindividual variability in semantic and letter fluency performance taking into account longitudinal annual assessments; and (b) establish predictive utility for intraindividual variability in semantic and letter fluency performance as a risk factor of incident MCI.
methodsParticipants were community-residing older adults (n = 514; M age = 75.89 ± 6.45; 55.1% female). Sixty participants were diagnosed with MCI at baseline and 50 developed incident MCI during the follow-up. We operationalized intraindividual variability as word generation slopes derived from 3 consecutive time intervals during the standard 1-min administration of both letter and semantic fluency tasks (i.e., 0-20 s, 21-40 s, and 41-60 s).
resultsLinear mixed effects models revealed significant within task slope effects for semantic (estimate = -8.350; p < .0001; 95% confidence interval [CI] = -8.604, -8.095) and letter (estimate = -5.068; p < .0001; 95% CI [-5.268, -4.869]) fluency indicating that word generation declined over the course of both tasks. The two-way interactions of MCI × Slope were significant for semantic (estimate = 1.34; p = .001; 95% CI [0.551, 2.126]) and letter (estimate = 0.733; p = .020; 95% CI [0.116, 1.350]) fluency indicating attenuated slopes among MCI participants compared to controls taking into account repeated annual assessments. Cox proportional-hazards models revealed that attenuated word generation slope, at baseline, in semantic (hazard ratio [HR] = 2.063; p = .015; 95% = 1.149 to 3.702) but not letter (HR = 0.704; p = .243; 95% CI [0.391, 1.269]) fluency was associated with increased risk of incident MCI.
conclusionIntraindividual variability in verbal fluency performance has clinical and predictive utility; it can be easily incorporated into testing batteries in clinical and research settings. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.