Evidence map›Paper›PMID 31192367›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2019

The number needed to benefit: estimating the value of predictive analytics in healthcare.

Vincent X Liu, David W Bates, Jenna Wiens, Nigam H Shah

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Early detection of adults ADHD using electronic health records: A machine learning study.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Conformal Prediction in Clinical Medical Sciences.Journal of healthcare informatics research · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A framework for making predictive models useful in practice.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vincent X LiuDivision of Research, Kaiser Permanente, Oakland, California, USA.
David W BatesDivision of General Internal Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.
Jenna WiensDivision of Computer Science and Engineering, College of Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Nigam H ShahDivision of Biomedical Informatics Research, Stanford University, Stanford, California, USA.

Funding

Methods for generalized ontology terms enrichment analysisR01LM011369 · NLM · STANFORD UNIVERSITY · PI SHAH, NIGAM H · 2013 to 2020
$5.0M
Identifying pre-sepsis opportunities for early, targeted intervention - Equipment SupplementR35GM128672 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI Vincent Liu · 2018 to 2026
$4.3M
NIGMS NIH HHS R35 GM128672NLM NIH HHS R01 LM011369
6 · The paper itself

Abstract

Predictive analytics in health care has generated increasing enthusiasm recently, as reflected in a rapidly growing body of predictive models reported in literature and in real-time embedded models using electronic health record data. However, estimating the benefit of applying any single model to a specific clinical problem remains challenging today. Developing a shared framework for estimating model value is therefore critical to facilitate the effective, safe, and sustainable use of predictive tools into the future. We highlight key concepts within the prediction-action dyad that together are expected to impact model benefit. These include factors relevant to model prediction (including the number needed to screen) as well as those relevant to the subsequent action (number needed to treat). In the simplest terms, a number needed to benefit contextualizes the numbers needed to screen and treat, offering an opportunity to estimate the value of a clinical predictive model in action.

Indexed as

Cost-Benefit AnalysisLearning Health SystemModels, TheoreticalDelivery of Health CareElectronic Health RecordsForecastingHumansMachine Learningcost-benefit analysisEHRimplementation sciencepredictive analytics

Identifiers

PMID31192367
PMCPMC6857505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.