ArticleJournal of immunology research2019
The Postembryonic Development of the Immunological Barrier in the Chicken Spleens.
Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Effects of dietary Zanthoxylum bungeanum seed powder on growth performance, immune function, and cecal microbiota in broilers.Poultry science · 2026Article
- Transcriptional Cytokine Responses Linked to Pathological Outcomes in Broiler Chickens Fed Residual Doses of Antimicrobials.International journal of molecular sciences · 2026Article
- Optimized amino acid ratios in reduced crude protein diets sustain broiler performance, gut health, and resilience to necrotic enteritis.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Research note: Impacts on turkey health when fed titrating reduced energy diets with an energy sparing feed additive.Poultry science · 2026Article
- Multidimensional regulatory mechanisms of chicken immunity: focus on viral infection, intestinal microbiota and heat stress.Frontiers in veterinary science · 2026Review
- Differential Expression of Key Immune Markers in the Intestinal Tract of Developing Chick Embryos.Veterinary sciences · 2025Article
- Comparative analysis of changes in immune cell in the chicken spleen across different ages using flow cytometry.BMC veterinary research · 2024Article
- Spirulina platensis as a growth booster for broiler; Insights into their nutritional, molecular, immunohistopathological, and microbiota modulating effects.BMC veterinary research · 2024Article
- Article
- Effects of blue-green LED lights with two perceived illuminance (human and poultry) on immune performance and skeletal development of layer chickens.Poultry science · 2022Article
- Early Nutrition with Different Diets Composition versus Fasting on Immunity-Related Gene Expression and Histomorphology of Digestive and Lymphoid Organs of Layer-Type Chicks.Animals : an open access journal from MDPI · 2021Article
- Morphological characterization of postembryonic development of blood-spleen barrier in duck.Poultry science · 2020Article
- Impact of Housing Environment on the Immune System in Chickens: A Review.Animals : an open access journal from MDPI · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The avian immune system improves with the development of the lymphoid organs. The chickens' spleen serves as the largest peripheral lymphoid organ, but little immunological research has been conducted on that spleen during postembryonic development. We investigated the blood-spleen barrier (BSB) by developing morphological architecture, resistance to the corpuscular antigen, immunocyte distribution, gene expression levels of TLR2/4 and cytokines in the spleens of hatched chickens of differing ages. Results demonstrated that the resistance of exogenous carbon particles of the BSB improved with the morphological and structural development of the chicken spleens. The cuboidal endothelial cells which lined the sheathed capillaries were gradually visible, and the discontinuous basement membrane was thickened during postembryonic development. There was an increased number of T and B cells and antigen-presenting cells in the chicken spleen between hatching and adulthood. The mRNA expression levels of TLR2/4, IL-2, IFN-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.