Evidence map›Paper›PMID 31192222›Full record

ArticleMolecular neuropsychiatry2019

Complex Neurological Phenotype in Female Carriers of

Matthew F Pescosolido, Brian C Kavanaugh, Nathalie Pochet, Michael Schmidt, Beth A Jerskey, Jeffrey M Rogg, Philip L De Jager, Tracy L Young-Pearse, Judy S Liu, Eric M Morrow

Open access · bronzeAbstract read
In one paragraph

Article in Molecular neuropsychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. The Recycling Endosomal (NaActa physiologica (Oxford, England) · 2026
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Neurology. Genetics · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Donor Splice Site Variant inMedicina (Kaunas, Lithuania) · 2022
    Article
  13. NovelNeurology. Genetics · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Matthew F PescosolidoDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
Brian C KavanaughDevelopmental Disorders Genetics Research Program, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University and Emma Pendleton Bradley Hospital, East Providence, Rhode Island, USA.
Nathalie PochetAnn Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
Michael SchmidtDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
Beth A JerskeyDevelopmental Disorders Genetics Research Program, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University and Emma Pendleton Bradley Hospital, East Providence, Rhode Island, USA.
Jeffrey M RoggDepartment of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Philip L De JagerAnn Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
Tracy L Young-PearseAnn Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
Judy S LiuDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
Eric M MorrowDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
Allen Institute for Brain Science · USBrown University · USBroad Institute · USBrigham and Women's Hospital · USProvidence College · US

Funding

Pathogenic Mechanisms in Christianson Syndrome and NHE6-Related DisordersR01NS113141 · NINDS · BROWN UNIVERSITY · PI Eric M Morrow · 2019 to 2026
$7.0M
Mechanisms of circuit failure and treatments in patient-derived neurons in autismR01MH105442 · NIMH · BROWN UNIVERSITY · PI MORROW, ERIC M · 2014 to 2019
$2.8M
Neuroscience Advanced Predoctoral Institutional Training GrantT32NS062443 · NINDS · BROWN UNIVERSITY · PI LIPSCOMBE, DIANE, MOORE, CHRISTOPHER I · 2008 to 2018
$1.8M
Autism-linked endosomal mechanisms in neuronal arborization and connectivityR01MH102418 · NIMH · BROWN UNIVERSITY · PI MORROW, ERIC M · 2015 to 2018
$1.6M
Endo-lysosomal mechanisms and treatment in atypical cerebellar neurodevelopmentF31NS093880 · NINDS · BROWN UNIVERSITY · PI PESCOSOLIDO, MATTHEW F. · 2016 to 2017
$88k
NIMH NIH HHS R01 MH102418NIMH NIH HHS R01 MH105442NINDS NIH HHS F31 NS093880NINDS NIH HHS R01 NS113141NINDS NIH HHS T32 NS062443
6 · The paper itself

Abstract

Mutations in

Indexed as

Christianson syndromeFemale carriersNa+/H+ exchanger 6 (NHE6)X-chromosome inactivation (XCI)

Identifiers

PMID31192222
PMCPMC6528080
OpenAlexW2921192849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.