Evidence map›Paper›PMID 31192200›Full record

ArticleFrontiers in bioengineering and biotechnology2019

Luminal Plasma Treatment for Small Diameter Polyvinyl Alcohol Tubular Scaffolds.

Grace Pohan, Pascale Chevallier, Deirdre E J Anderson, John W Tse, Yuan Yao, Matthew W Hagen, Diego Mantovani, Monica T Hinds, Evelyn K F Yim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Grace PohanDepartment of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
Pascale ChevallierLaboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering, CHU de Québec Research Center, Regenerative Medicine, Laval University, Québec City, QC, Canada.
Deirdre E J AndersonDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States.
John W TseDepartment of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
Yuan YaoDepartment of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
Matthew W HagenDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States.
Diego MantovaniLaboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering, CHU de Québec Research Center, Regenerative Medicine, Laval University, Québec City, QC, Canada.
Monica T HindsDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States.
Evelyn K F YimDepartment of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
University of Waterloo · CAOregon Health & Science University · USUniversité Laval · CA

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Contact Pathway Activation on Vascular DevicesR01HL144113 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, MCCARTY, OWEN J · 2018 to 2025
$6.0M
Surface Modification Compliant Vascular GraftsR01HL130274 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, YIM, EVELYN KING FAI · 2016 to 2019
$2.6M
Microengineering the Dental Pulp Vascular Microenvironment_Diversity SupplementR01DE026170 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BERTASSONI, LUIZ EDUARDO · 2016 to 2020
$2.5M
NHLBI NIH HHS R01 HL130274NHLBI NIH HHS R01 HL144113NIDCR NIH HHS R01 DE026170NIH HHS P51 OD011092
6 · The paper itself

Abstract

Plasma-based surface modification is recognized as an effective way to activate biomaterial surfaces, and modulate their interactions with cells, extracellular matrix proteins, and other materials. However, treatment of a luminal surface of a tubular scaffold remains non-trivial to perform in small diameter tubes. Polyvinyl alcohol (PVA) hydrogel, which has been widely used for medical applications, lacks functional groups to mediate cell attachment. This poses an issue for vascular applications, as endothelialization in a vascular graft lumen is crucial to maintain long term graft patency. In this study, a Radio Frequency Glow Discharges (RFGD) treatment in the presence of NH

Indexed as

ammoniaendothelializationhydrogelradio-frequencystability

Identifiers

PMID31192200
PMCPMC6541113
OpenAlexW2943910759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.