Evidence map›Paper›PMID 31192141›Full record

ArticleJournal of comorbidity

Impact of cardiac- and noncardiac-related conditions on adverse outcomes in patients hospitalized with acute myocardial infarction.

Mayra Tisminetzky, Jerry H Gurwitz, Ruben Miozzo, Joel M Gore, Darleen Lessard, Jorge Yarzebski, Robert J Goldberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of comorbidity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mayra TisminetzkyMeyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0002-8557-2029
Jerry H GurwitzMeyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Ruben MiozzoJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Joel M GoreDepartment of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Darleen LessardDepartment of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Jorge YarzebskiDepartment of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Robert J GoldbergMeyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA.

Funding

Multimorbidity and Treatment-Related Outcomes in Older Heart Failure PatientsR01AG062630 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TISMINETZKY, MAYRA S. · 2019 to 2022
$2.4M
NIA NIH HHS R01 AG062630
6 · The paper itself

Abstract

backgroundTo examine the impact of cardiac- and noncardiac-related conditions on the risk of hospital complications and 7- and 30-day rehospitalizations in older adult patients with an acute myocardial infarction (AMI). METHODS AND

resultsThe study population consisted of 3863 adults aged 65 years and older hospitalized with AMI in Worcester, Massachusetts, during six annual periods between 2001 and 2011. Individuals were categorized into four groups based on the presence of 11 previously diagnosed cardiac and noncardiac conditions. The median age of the study population was 79 years and 49% were men. Twenty-eight percent of patients had two or less cardiac- and no noncardiac-related conditions, 21% had two or less cardiac and one or more noncardiac conditions, 20% had three or more cardiac and no noncardiac conditions, and 31% had three or more cardiac and one or more noncardiac conditions. Individuals who presented with one or more noncardiac-related conditions were less likely to have been prescribed evidence-based medications and/or to have undergone coronary revascularization procedures than patients without any noncardiac condition. After multivariable adjustment, individuals with three or more cardiac and one or more noncardiac conditions were at greatest risk for all adverse outcomes.

conclusionsOlder patients hospitalized with AMI carry a significant burden of cardiac- and noncardiac-related conditions. Older adults who presented with multiple cardiac and noncardiac conditions experienced the worse short-term outcomes and treatment strategies should be developed to improve their in-hospital and post-discharge care and outcomes.

Indexed as

Chronic conditionsmyocardial infarction

Identifiers

PMID31192141
PMCPMC6542121

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.