ReviewJournal of ophthalmology2019
Pathogenesis and Management of Macular Hole: Review of Current Advances.
Review in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 75 citations in OpenAlex.
- Retinal glial cell removing during internal limiting membrane peeling is associated with higher-stage idiopathic epiretinal membrane.Eye and vision (London, England) · 2026Article
- First-in-human application of decellularized human amniotic membrane hydrogel as an injectable intraocular scaffold for large idiopathic full-thickness macular hole closure: four-month clinical outcomes.International journal of retina and vitreous · 2026Article
- Macular hole detection and segmentation on fundus photography using large multimodal generative models for synthetic augmentation.BMC ophthalmology · 2026Article
- Neurosymbolic AI Framework for Explainable Retinal Disease Classification From OCT Images.Translational vision science & technology · 2026Article
- Visual and anatomical outcomes of full-thickness macular hole surgery and associated factors in selected hospitals in Tanzania.PloS one · 2026Article
- Novel TA-IVIZ Patch and BSS Tamponade for Macular Hole Repair: A Pilot Study.Translational vision science & technology · 2025Article
- A study on postural care after macular hole surgery based on a novel positioning sensor.Scientific reports · 2025Article
- New surgery technique for refractory macular hole guided by intraoperative OCT: free internal limiting membrane flap and autologous blood clot.International journal of retina and vitreous · 2025Article
- Expanding Application of Optical Coherence Tomography Beyond the Clinic: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Refractory Macular Hole with Retinal Detachment Treated with Autologous Retinal Transplantation: A Case Report.Korean journal of ophthalmology : KJO · 2025Article
- Bilateral Simultaneous Full-Thickness Macular Holes: A Case Report with Spontaneous Resolution.Reports (MDPI) · 2025Article
- Combined Surgically Induced Macular Detachment and Autologous Internal Limiting Membrane Transplantation for Refractory Full Thickness Macular Hole.Journal of clinical medicine · 2025Article
- Management of traumatic macular hole and retinal detachment using amniotic membrane transplantation: A case report.American journal of ophthalmology case reports · 2025Article
- Supervised machine learning statistical models for visual outcome prediction in macular hole surgery: a single-surgeon, standardized surgery study.International journal of retina and vitreous · 2025Article
- Phacovitrectomy vs. consecutive vitrectomy for idiopathic macular holes: short and long-term outcomes and OCT image quality assessment.International journal of retina and vitreous · 2024Article
- Evaluating deep learning models for classifying OCT images with limited data and noisy labels.Scientific reports · 2024Article
- Comparative analysis of pre-operative findings and post-operative outcomes in primary and secondary macular holes at a tertiary eye hospital in South India.International journal of retina and vitreous · 2024Article
- Large macular hole and autologous retinal transplantation: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Self-supervised contrastive learning improves machine learning discrimination of full thickness macular holes from epiretinal membranes in retinal OCT scans.PLOS digital health · 2024Article
- Effect of internal limiting membrane surgical techniques on the idiopathic and refractory management of macular holes: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Macular hole has been believed to be a disorder of vitreomacular interface, which forms as a result of abnormal vitreous traction from incomplete vitreous detachment. However, our recent studies demonstrated that dynamic forces, caused by mobile posterior cortical vitreous with fluid currents, exist already at early stages of macular hole development. Therefore, in eyes with flexible vitreous, the contributions of tractional forces due to vitreous shrinkage are unlikely. These facts indicate that in the development of idiopathic macular holes, there is a greater contribution of dynamic forces than has been previously reported. This review also evaluates the recent findings in the assessment of the idiopathic macular holes and the recent therapeutic strategies for optimal management. Inner limiting membrane is considered to improve anatomical closure rate; however, it is still questionable if peeling is necessary in holes less than 250
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.