Evidence map›Paper›PMID 31191916›Full record

ArticleJournal of virus eradication2019

Revisiting the 'sterilising cure' terminology: a call for more patient-centred perspectives on HIV cure-related research.

Luke Newton, Raúl Necochea, David Palm, Jeff Taylor, Liz Barr, Hursch Patel, Anshula Nathan, Jo Gerrard, Laurie Sylla, Brandon Brown and 1 more

Abstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Time for a globally unified chronic HBV terminology?JHEP reports : innovation in hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luke NewtonUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Raúl NecocheaDepartment of Social Medicine, UNC School of Medicine, Chapel Hill, NC, USA.
David PalmGlobal HIV Prevention and Treatment Unit Clinical Trials Community Advisory Board, University of North Carolina at Chapel Hill, NC, USA.
Jeff TaylorCollaboratory of AIDS Researchers for Eradication (CARE) Community Advisory Board, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Liz BarrAIDS Clinical Trials Group (ACTG) Scientific Sub-Committee Representative, John Hopkins University, Baltimore, MD, USA.
Hursch PatelUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Anshula NathanUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.
Jo GerrardUniversity of California Riverside School of Medicine, Riverside, CA, USA.
Laurie SylladefeatHIV Community Advisory Board, Seattle, WA, USA.
Brandon BrownCenter for Healthy Communities, Department of Social Medicine, Population and Public Health, University of California Riverside School of Medicine, Riverside, CA, USA.
Karine DubéUNC Gillings School of Global Public Health, Chapel Hill, NC, USA.

Funding

Cell and Gene Therapy for HIV CureUM1AI126623 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JEROME, KEITH R, KIEM, HANS-PETER · 2016 to 2020
$24.2M
NIAID NIH HHS UM1 AI126623
6 · The paper itself

Abstract

The literature on HIV therapeutics research is rife with terminology associating 'sterilisation' with HIV cure. We find connotations of the word 'sterilising' problematic for the HIV cure research field. In this viewpoint, we review associations of sterilising with concepts of disinfection or cleansing, as well as coerced sterilisation. We discuss emerging findings from socio-behavioural research that show aversion from people living with HIV towards the 'sterilising cure' nomenclature. We call for more collaborations with people with HIV as partners to help define what would be a more acceptable terminology for describing an HIV cure.

Indexed as

HIV cure researchpatient centrednesssterilising cureterminology

Identifiers

PMID31191916
PMCPMC6543486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.