ArticleChemical science2019
Sequence information transfer using covalent template-directed synthesis.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Finding REMO: a sequencing method for recognition-encoded melamine oligomers.Chemical science · 2026Article
- Sequence-Controlled Neutral-Ionic Multiblock-Like Copolymers through Switchable PIESA in a One-Pot Approach.ACS macro letters · 2025Article
- Covalent Template-Directed Synthesis: A Powerful Tool for the Construction of Complex Molecules.Chemical reviews · 2025Review
- Length and Sequence-Selective Polymer Synthesis Templated by a Combination of Covalent and Noncovalent Base-Pairing Interactions.Journal of the American Chemical Society · 2024Article
- Replication of synthetic recognition-encoded oligomers by ligation of trimer building blocks.Organic chemistry frontiers : an international journal of organic chemistry · 2023Article
- Sequence-selective duplex formation and template effect in recognition-encoded oligoanilines.Chemical science · 2023Article
- Supramolecular template-directed synthesis of triazole oligomers.Chemical science · 2022Article
- Effect of backbone flexibility on covalent template-directed synthesis of linear oligomers.Organic & biomolecular chemistry · 2022Article
- Replication of a synthetic oligomer using chameleon base-pairs.Chemical communications (Cambridge, England) · 2022Article
- H-Bond Templated Oligomer Synthesis Using a Covalent Primer.Journal of the American Chemical Society · 2022Article
- An Orthogonal Dynamic Covalent Chemistry Tool for Ring-Opening Polymerization of Cyclic Oligochalcogenides on Detachable Helical Peptide Templates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Replication of Sequence Information in Synthetic Oligomers.Accounts of chemical research · 2021Article
- Controlled mutation in the replication of synthetic oligomers.Chemical science · 2021Article
- Solid-Phase Synthesis of Sequence-Defined Informational Oligomers.The Journal of organic chemistry · 2020Article
- Single-site binding of pyrene to poly(ester-imide)s incorporating long spacer-units: prediction of NMR resonance-patterns from a fractal model.Chemical science · 2020Article
- Two-component assembly of recognition-encoded oligomers that form stable H-bonded duplexes.Chemical science · 2020Article
- Cap control: cyclicRSC advances · 2019Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Template-directed synthesis is the biological method for the assembly of oligomers of defined sequence, providing the molecular basis for replication and the process of evolution. To apply analogous processes to synthetic oligomeric molecules, methods are required for the transfer of sequence information from a template to a daughter strand. We show that covalent template-directed synthesis is a promising approach for the molecular replication of sequence information in synthetic oligomers. Two monomer building blocks were synthesized: a phenol monomer and a benzoic acid monomer, each bearing an alkyne and an azide for oligomerization
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Registered trials
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