Evidence map›Paper›PMID 31191849›Full record

ArticleFacts, views & vision in ObGyn2018

Correlation between Adenomyosis and Endometrial cancer: 6-year experience of a single center.

D Zouzoulas, D Tsolakidis, I Efstratiou, S Pervana, E Pazarli, G Grimbizis

Erratum issuedAbstract read
In one paragraph

Article in Facts, views & vision in ObGyn, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Ectopic Endometrium: The Pathologist's Perspective.International journal of molecular sciences · 2021
    Review
  5. Review
  6. Origin and Pathogenic Mechanisms of Uterine Adenomyosis: What Is Known So Far.Reproductive sciences (Thousand Oaks, Calif.) · 2021
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

D ZouzoulasDepartment of Obstetrics & Gynecology, Aristotle University of Thessaloniki, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.
D TsolakidisDepartment of Obstetrics & Gynecology, Aristotle University of Thessaloniki, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.
I EfstratiouAnatomical Pathology Laboratory, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.
S PervanaAnatomical Pathology Laboratory, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.
E PazarliAnatomical Pathology Laboratory, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.
G GrimbizisDepartment of Obstetrics & Gynecology, Aristotle University of Thessaloniki, "Papageorgiou" Hospital, Thessaloniki, 56403, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdenomyosis often co-exists in the pathological specimens after surgery for endometrial cancer. The aim of this study is to describe the clinicopathological and oncological characteristics of these patients and further investigate the possibility of malignant transformation in the adenomyotic tissue.

methodsWe retrospectively reviewed the medical records of all patients that underwent hysterectomy for endometrial cancer (January 2012 - December 2017). The pathological reports were studied and when adenomyosis was present, the pathological slides were reviewed in order to discover any malignant change in the adenomyotic tissue. The clinicopathological characteristics and oncological results were described.

resultsOut of 229 cases of endometrial cancer, 64 (28%) patients had concurrently endometrial cancer and adenomyosis. Among these 64 patients, 7 (11%) had malignant transformation of adenomyosis. The mean age of patients suffering from both endometrial cancer and adenomyosis was 63.2 years old and 57 (89%) of these patients, had early endometrial cancer. Concerning the patients with malignant transformation of adenomyosis, their mean age was 65 years old with no premenopausal case. DISCUSSION: Adenomyosis has been described in the last decades, but its malignant transformation into endometrial cancer is not fully undercovered. Further investigation is needed in order to clarify the pathologic progression of adenomyotic lesions to endometrial cancer.

Indexed as

Adenomyosisconcurrenceendometrial cancermalignant transformation

Identifiers

PMID31191849
PMCPMC6548412

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.